How far is Orlando from Lake City?

The distance between the two cities is 137 miles (221 km).

What are the departure and arrival stations when taking the bus from Orlando to Lake City?

Most of the buses traveling from Orlando to Lake City leave from Orlando Bus Station and arrive at Lake City Bus Stop. These are the primary departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.

Bus Orlando to Lake City from $33 | Refundable Tickets

Previously seen trips

Next departures for Orlando to Lake City on November 23
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound	Bus	4:45am	Orlando Bus Station	4h 30m	9:15am	Lake City Bus Station	No tags
	Bus	5:15am	Orlando Bus Station	3h 45m	9:00am	Lake City Bus Station	No tags
	Bus	9:55am	Orlando Bus Station	3h 30m	1:25pm	Lake City Bus Station	No tags
	Bus	1:00pm	Orlando Bus Station	4h 5m	5:05pm	Lake City Bus Station	No tags
Greyhound + FlixBus	Bus	4:45am	Orlando Bus Station	4h 30m	9:15am	Lake City Bus Station	No tags

Get from Orlando to Lake City

This route is served by bus only

The journey takes about 3 hours 45 minutes and with fares starting at just $34, it presents an excellent value for a comfortable ride.

3bus per day

3h 45mAverage Duration

135 milesDistance

5kgCO₂ emissions

Where are the popular stops in Orlando and Lake City?

Stops in Orlando

A
Orlando Bus Station
555 N John Young Pkwy, Orlando, FL 32805
Visit page
B
Orlando RedCoach Station
RedCoach Station, 1777 McCoy Road, Orlando, FL 32809
Visit page
C
Jet Set Express Terminal
Jet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States
Visit page
D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830
E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA
F
Seaworld Hotels
10100 International Drive , Orlando, 32821

Stops in Lake City

A
Lake City Bus Stop
2470 W US HWY 90, Lake City, FL 32025, USA
Visit page
B
Lake City Greyhound Bus Station
251 S MARION AVE , 32055, Florida

Compare bus companies

FlixBus

3.5/511,414 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,392 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Orlando to Lake City by bus

How far is Orlando from Lake City?
What are the departure and arrival stations when taking the bus from Orlando to Lake City?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/21

$40

11/22

$43

Today

No data

11/24

No data

11/25

No data

11/26

No data

11/27

$35

11/28

No data

The cheapest trip from Orlando to Lake City was searched and found on Nov 27, 2025 with a price of $35

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Lake City, as early as possible.

You can expect to pay from $35 to $52 for a bus ticket from Orlando to Lake City based on the last 2 days. You can expect to find the cheapest price for the trip at $35 which is on 2025-11-27.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.