Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Lake City Bus Station | Jacksonville Bus Station | CheapestFastest |
Last refresh of the prices: Yesterday at 3:27 PM EST.
Get from Lake City to Jacksonville
The journey takes about 1 hour 5 minutes and with fares starting at just $22, it presents an excellent value for a comfortable ride.
Where are the popular stops in Lake City and Jacksonville?
Stops in Lake City
- A2470 W US HWY 90, Lake City, FL 32025, USA
- B
Lake City Greyhound Bus Station
251 S MARION AVE , 32055, Florida
Stops in Jacksonville
- A3570 Clifford Ln, Jacksonville, FL 32209, USA
- B
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA - C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207 - D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Lake City Jacksonville recent customer reviews
Great bus, great bus service. Driver was a good driver also. Maybe a little more upbeat. Good morning, enjoy the rest of your trip, stuff like that. Overall very pleasantly experience:)
Timothy M.
Frequently asked questions about traveling from Lake City to Jacksonville, FL by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Lake City to Jacksonville?
The cheapest bus tickets from Lake City to Jacksonville start from $22. The average price for this route is around $27. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Lake City to Jacksonville?
The average bus trip duration from Lake City to Jacksonville is 1h 5m, covering a distance of 59 miles (94 km). The quickest bus can get you there in 1h 5m and is operated by Greyhound.
Which bus companies service the Lake City to Jacksonville route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Lake City to Jacksonville?
The earliest bus departs from Lake City to Jacksonville at 2:00pm. And the latest bus departs at 7:30pm.
What are the CO₂ emissions for the bus trip from Lake City to Jacksonville?
A bus trip from Lake City to Jacksonville generates an estimated 2 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Lake City to Jacksonville, FL was searched and found on Nov 28, 2025 with a price of $15To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lake City to Jacksonville, FL, as early as possible.
You can expect to pay from $15 to $49 for a bus ticket from Lake City to Jacksonville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at $15 which is on 2025-11-28.
