Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Lake City Bus Station | Orlando Bus Station | CheapestFastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Lake City Bus Station | Orlando Bus Station | No tags |
Last refresh of the prices: Yesterday at 3:14 AM EST.
Get from Lake City to Orlando
The journey takes about 4 hours 29 minutes and with fares starting at just $35, it presents an excellent value for a comfortable ride.
Where are the popular stops in Lake City and Orlando?
Stops in Lake City
- A2470 W US HWY 90, Lake City, FL 32025, USA
- B
Lake City Greyhound Bus Station
251 S MARION AVE , 32055, Florida
Stops in Orlando
- A555 N John Young Pkwy, Orlando, FL 32805
- BRedCoach Station, 1777 McCoy Road, Orlando, FL 32809
- CJet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States
- D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830 - E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA - F
Seaworld Hotels
10100 International Drive , Orlando, 32821
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Frequently asked questions about traveling from Lake City to Orlando by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Lake City to Orlando?
The cheapest bus tickets from Lake City to Orlando start from $35. The average price for this route is around $56. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Lake City to Orlando?
The average bus trip duration from Lake City to Orlando is 4h 29m, covering a distance of 135 miles (218 km). The quickest bus can get you there in 3h 15m and is operated by FlixBus.
Which bus companies service the Lake City to Orlando route?
What is the earliest and latest departure time for the bus from Lake City to Orlando?
The earliest bus departs from Lake City to Orlando at 2:00pm. And the latest bus departs at 7:30pm.
What are the CO₂ emissions for the bus trip from Lake City to Orlando?
A bus trip from Lake City to Orlando generates an estimated 5 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Lake City to Orlando?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.
Which bus company has the best Wi-Fi from Lake City to Orlando?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Lake City to Orlando?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Lake City to Orlando?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Lake City to Orlando was searched and found on Dec 3, 2025 with a price of $31To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lake City to Orlando, as early as possible.
You can expect to pay from $31 to $90 for a bus ticket from Lake City to Orlando based on the last 2 days. You can expect to find the cheapest price for the trip at $31 which is on 2025-12-03.
