Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Tampa Bus Station | Lake City Bus Station | Cheapest | ||||
 | Bus | Tampa Bus Station | Lake City Bus Station | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Tampa Bus Station | Lake City Bus Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | University of South Florida | Lake City Bus Station | No tags |
Last refresh of the prices: Today at 16:10 EST.
Get from Tampa to Lake City
The journey takes about 10 hours 25 minutes, and with fares starting at just £24, it presents an excellent value for a comfortable ride.
Where are the popular stops in Tampa and Lake City?
Stops in Tampa
- A
Tampa 13th Avenue Bus Stop (McDonald's)
2101 E 13th Ave (McDonald's), Tampa, FL 33605 - B
Tampa USF, FL
3801 USF Holly Drive, Tampa., FL 33620, USA - C
Greyhound Station
610 E Polk St, Tampa, FL 33602, USA - D
E Sligh Ave
11555 E Sligh Ave, Seffner, FL 33584, USA - E
N Marion St & E Laurel St
551 E Laurel St, Tampa, FL 33602, USA - F
Port of Tampa
200-298 FL-60, Tampa, FL 33602, USA
Stops in Lake City
- A2470 W US HWY 90, Lake City, FL 32025, USA
- B
Lake City Greyhound Bus Station
251 S MARION AVE , 32055, Florida
Compare bus companies
Frequently asked questions about travelling by bus from Tampa to Lake City
How far is Lake City from Tampa by coach?
The distance between Tampa and Lake City by coach is approximately 155 miles (250 km).
Is there a way to reach Lake City from Tampa without a car?
The best way to go from Tampa to Lake City without a car is by coach. They are frequent and reliable, offering a convenient and eco-friendly journey. Depending on your preferences, another alternative is to explore ridesharing trips.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tampa to Lake City was searched and found on 24 Nov 2025 with a price of £25To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tampa to Lake City as early as possible.
You can expect to pay from £25 to £57 for a bus ticket from Tampa to Lake City based on the last 2 days. You can expect to find the cheapest price for the trip at £47, which is on 2025-11-29.
