Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound St. Louis Columbia recent customer reviews
I was put in an old, smelly taxi cab with 2 other passengers for my almost 3 hour trip with no explanation as to why we were not on the bus.
Frequently asked questions about traveling from St. Louis to Columbia, MO by bus
What is the travel distance from St. Louis to Columbia?
About 118 miles (189 km) separate St. Louis and Columbia.
What are the departure and arrival stations when taking the bus from St. Louis to Columbia?
Buses going from St. Louis to Columbia start their journey at Gateway Station and reach their destination at Midway Truck Plaza Bus Stop.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/20
$36
11/21
$44
Today
$39
11/23
$39
11/24
$29
11/25
$28
11/26
$32
11/27
$30
The cheapest trip from St. Louis to Columbia, MO was searched and found on Nov 25, 2025 with a price of $28
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Columbia, MO, as early as possible.
You can expect to pay from $28 to $64 for a bus ticket from St. Louis to Columbia, MO based on the last 2 days. You can expect to find the cheapest price for the trip at $28 which is on 2025-11-25.
The cheapest trip from St. Louis to Columbia, MO was searched and found on Nov 25, 2025 with a price of $28
