Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Downtown Greyhound Station | Midway Truck Plaza Bus Stop | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Downtown Greyhound Station | Midway Truck Plaza Bus Stop | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Downtown Greyhound Station | Midway Truck Plaza Bus Stop | No tags | ||||
| Bus | Downtown Greyhound Station | Columbia Wabash Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Downtown Greyhound Station | Columbia Wabash Station | No tags |
Last refresh of the prices: Last Friday at 2:10 PM CST.
Get from Chicago to Columbia
The journey takes about 14 hours 50 minutes and with fares starting at just $56, it presents an excellent value for a comfortable ride.
Where are the popular stops in Chicago and Columbia?
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Frequently asked questions about traveling from Chicago to Columbia, MO by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Chicago to Columbia?
The cheapest bus tickets from Chicago to Columbia start from $56. The average price for this route is around $107. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Chicago to Columbia?
The average bus trip duration from Chicago to Columbia is 14h 50m, covering a distance of 316 miles (510 km). The quickest bus can get you there in 12h 10m and is operated by Greyhound.
Which bus companies service the Chicago to Columbia route?
What is the earliest and latest departure time for the bus from Chicago to Columbia?
The earliest bus departs from Chicago to Columbia at 12:15am. And the latest bus departs at 11:50pm.
What are the CO₂ emissions for the bus trip from Chicago to Columbia?
A bus trip from Chicago to Columbia generates an estimated 13 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Chicago to Columbia?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.
Which bus company has the best Wi-Fi from Chicago to Columbia?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Chicago to Columbia?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Chicago to Columbia?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to Columbia, MO was searched and found on Jan 10, 2026 with a price of $54To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Columbia, MO, as early as possible.
You can expect to pay from $54 to $123 for a bus ticket from Chicago to Columbia, MO based on the last 2 days. You can expect to find the cheapest price for the trip at $54 which is on 2026-01-10.
