Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Midway Truck Plaza Bus Stop | Gateway Station | Cheapest | ||||
| Bus | Midway Truck Plaza Bus Stop | Gateway Station | Fastest | ||||
| Bus | Midway Truck Plaza Bus Stop | Gateway Station | No tags | ||||
| Bus | Columbia Wabash Station | Gateway Station | No tags | ||||
| Bus | Columbia Wabash Station | Gateway Station | No tags |
Last refresh of the prices: Today at 10:04 AM CST.
Get from Columbia to St. Louis
The journey takes about 2 hours 50 minutes and with fares starting at just $28, it presents an excellent value for a comfortable ride.
Where are the popular stops in Columbia and St. Louis?
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Columbia St. Louis recent customer reviews
This Greyhound experience was not great. The bus was late and there was no communication about status while at the partner station. The drivers talked loudly for the duration of the trip which was exhausting to listen to even though I wasn’t sitting anywhere near them.
Naya O.
Bus driver was nasty , vindictive and rude. I may never ride grey hound again because of him.
Rafael R.
1-the bus was cancelled 2- no one contact me even thought my email associated with ticket 3- wouldn't know that bus cancelled if won't spent about 1 hour on phone 4- bad service
Michelle G.
Frequently asked questions about traveling from Columbia, MO to St. Louis by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Columbia, MO to St. Louis was searched and found on Nov 29, 2025 with a price of $27To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbia, MO to St. Louis, as early as possible.
You can expect to pay from $27 to $89 for a bus ticket from Columbia, MO to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $27 which is on 2025-11-29.
