Based on 82 reviews, the company was rated 3.9 stars on Busbud. Travelers were especially satisfied with the departure location and the cleanliness but often complained with the wifi. Pluss Chile ticket prices on this trip start at $37
Based on 13 reviews, the company was rated 3.6 stars on Busbud. Travelers were especially satisfied with the seats and the temperature but often complained with the timeliness. Pullman San Andres ticket prices on this trip start at $36
Based on 125 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the staff and the ticket access but often complained with the wifi. Cikbus Elité ticket prices on this trip start at $27
Cikbus Elité / Ciktur Santiago Antofagasta recent customer reviews
Smooth and safe bus ride from Santiago to Antofagasta.
Small issues:
Bus arrived late.
No chargers on the bus.
No toilet tissue in toilet, as well as no water and soap in toilet to wash hands after use.
Based on 54 reviews, the company was rated 4.2 stars on Busbud. Travelers were especially satisfied with the ticket access and the seats but often complained with the wifi. Buses Andimar ticket prices on this trip start at $35
Based on 19 reviews, Condor Bus was rated 3.6 stars for this trip. Condor Bus ticket prices on this trip start at $30, with the trip lasting on average 1216.
Based on 52 reviews, the company was rated 3.8 stars on Busbud. Travelers were especially satisfied with the departure location and the ticket access but often complained with the wifi. Buses Romani ticket prices on this trip start at $36
Based on 12 reviews, Serena Mar was rated 4 stars for this trip. Serena Mar ticket prices on this trip start at $63, with the trip lasting on average 1139.
Based on 70 reviews, the company was rated 3 stars on Busbud. Travelers were especially satisfied with the timeliness and the departure location but often complained with the wifi. Buses Paravias ticket prices on this trip start at $47
Based on 3 reviews, the company was rated 4.3 stars on Busbud. Travelers were especially satisfied with the staff and the timeliness but often complained with the wifi. Clikbus ticket prices on this trip start at $30
Frequently asked questions about traveling from Santiago, CL to Antofagasta by bus
What is the travel distance from Santiago to Antofagasta?
The distance separating Santiago and Antofagasta is 677 miles (1091 km).
What are the departure and arrival stations when taking the bus from Santiago to Antofagasta?
The majority of buses traveling from Santiago to Antofagasta start their journey at San Borja and wind up at Terminal Antofagasta. These are the main pick-up and drop-off locations on this route, but you can also find other options that could better fit your plans.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/25
$36
11/26
$36
Today
$33
11/28
$26
11/29
$26
11/30
$33
12/01
$26
12/02
$26
The cheapest trip from Santiago, CL to Antofagasta was searched and found on Dec 2, 2025 with a price of $26
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago, CL to Antofagasta, as early as possible.
You can expect to pay from $26 to $66 for a bus ticket from Santiago, CL to Antofagasta based on the last 2 days. You can expect to find the cheapest price for the trip at $26 which is on 2025-12-02.
Usually Pluss Chile will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.