Bus from Santiago, CL to Antofagasta: Tickets & Timetables

Next bus departures

Next departures from Santiago to Antofagasta on 7 January
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AndimarBus
    Terminal San Borja
    Terminal de Buses Cardenal Carlos Oviedo Cavada)Cheapest
    Cikbus ElitéBus
    Terminal de Buses San Borja - San Francisco de Borja
    Terminal AntofagastaFastest
    Cikbus ElitéBus
    Terminal de Buses San Borja - San Francisco de Borja
    Terminal AntofagastaNo tags
    Pluss ChileBus
    San Borja
    Terminal AntofagastaNo tags
    AndimarBus
      Terminal San Borja
      Terminal de Buses Cardenal Carlos Oviedo Cavada)No tags

      Last refresh of the prices: Today at 10:12 PM -03.

      Get from Santiago to Antofagasta

      This route is served by bus only

      The journey takes about 18 hours 40 minutes, and with fares starting at just R 461, it presents an excellent value for a comfortable ride.

      50bus per day
      18h 40mAverage duration
      1095 kmDistance
      27kgCO₂ emissions

      Frequently asked questions about travelling from Santiago, CL to Antofagasta by bus

      Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

      1. How much is the bus ticket from Santiago to Antofagasta?

        The cheapest bus tickets from Santiago to Antofagasta start at R 461. The average price for this route is around R 821. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

      2. How long is the bus journey from Santiago to Antofagasta?

        The average bus journey time from Santiago to Antofagasta is 18h 40m, covering a distance of 1095 km. The fastest bus gets you there in 17h 15m and is operated by Cikbus Elité.

      3. Which bus companies service the Santiago to Antofagasta route?

        Several major bus companies operate on this route with 50 buses available per day, including services from Pluss Chile, Cikbus Elité, Pullman San Andres, Buses Andimar, Buses Evans, Condor Bus, Buses Romani, Serena Mar, Buses Paravias.

      4. What is the earliest and latest departure time for the bus from Santiago to Antofagasta?

        The earliest bus departs from Santiago to Antofagasta at 06:15. And the latest bus departs at 23:59.

      5. What are the CO₂ emissions for the bus trip from Santiago to Antofagasta?

        A bus trip from Santiago to Antofagasta produces an estimated 27 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

      6. What is the best bus company from Santiago to Antofagasta?

        According to Busbud customers, the highest-rated bus company on this route is Buses Andimar, with an average rating of 4.1 out of 5 stars based on 56 reviews.

      7. Which bus company has the best Wi-Fi from Santiago to Antofagasta?

        Based on reviews on Busbud, the bus company Buses Paravias has the best Wi-Fi rating with a score of 1.8.

      8. Which bus company offers the most punctual service from Santiago to Antofagasta?

        According to Busbud traveller reviews, the most punctual bus company on this route is Buses Romani, with a punctuality rating of 4.5 out of 5 stars.

      9. Which bus company has the cleanest buses from Santiago to Antofagasta?

        According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Pluss Chile, with a cleanliness rating of 4.5 out of 5 stars.

      Find cheapest prices for buses

      Price is for a one-way ticket for one passenger and based on past searches.

      Best price found
      02/01
      R 888
      03/01
      R 764
      Today
      R 775
      05/01
      R 843
      06/01
      R 773
      07/01
      R 662
      08/01
      R 519
      09/01
      R 517
      busbud logoThe cheapest trip from Santiago, CL to Antofagasta was searched and found on 09 Jan 2026 with a price of R 517

      To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago, CL to Antofagasta as early as possible.

      You can expect to pay from R 517 to R 1 026 for a bus ticket from Santiago, CL to Antofagasta based on the last 2 days. You can expect to find the cheapest price for the trip at R 517, which is on 2026-01-09.

      Usually Pluss Chile will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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