Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Terminal San Borja | Calama (Terminale de buses Granaderos) | Cheapest | |||||
 | San Borja | Av. Balmaceda | Fastest | |||||
| San Borja | Av. Balmaceda | No tags | |||||
| Terminal San Borja | Calama (Terminale de buses Granaderos) | No tags | |||||
Flixbus Chile + Andimar | Santiago (Los Libertadores) | Calama (Terminale de buses Granaderos) | No tags |
Last refresh of the prices: Yesterday at 10:24 PM -03.
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Get from Santiago to Calama
The journey takes about 22 hours 55 minutes, and with fares starting at just US$36, it presents an excellent value for a comfortable ride.
Bus Santiago, CL to Calama: Trip Overview
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Santiago to Calama Bus
With Busbud, comparing and booking tickets for a bus from Santiago to Calama is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from Santiago to Calama will be provided by the most trusted bus companies.
Discover how much the bus trip from Santiago to Calama will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Santiago and Calama?
Frequently asked questions on the trip Santiago, CL - Calama
How much does a bus ticket from Santiago to Calama cost?
The bus ticket price from Santiago to Calama starts at US$36. The best way to find cheap bus tickets from Santiago to Calama is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Santiago to Calama?
The average travel time between Santiago and Calama is around 22h 55m, although the fastest bus will take about 21h 40m. This is the time it takes to travel the 1232 km that separates the two cities.
How many daily bus connections are there between Santiago and Calama?
The number of buses from Santiago to Calama can differ depending on the day of the week. On average, there are 22 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Santiago to Calama by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Santiago to Calama?
When taking the bus from Santiago to Calama, you can travel comfortably and safely with Pluss Chile, Cikbus Elité, Buses Andimar.
What are the departure and arrival stations when taking the bus from Santiago to Calama?
Buses travelling between Santiago and Calama leave from San Borja or Terminal Sur and arrive at Av. Balmaceda, Calama, Parada de Autobuses de Calama - Ascotan.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santiago, CL to Calama was searched and found on 06 Nov 2025 with a price of US$36To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago, CL to Calama as early as possible.
You can expect to pay from US$36 to US$53 for a bus ticket from Santiago, CL to Calama based on the last 2 days. You can expect to find the cheapest price for the trip at US$36, which is on 2025-11-06.
Usually Pluss Chile will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Santiago to Calama.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from Santiago to Calama, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Santiago to Calama will emit half the CO2 emitted by a train, and radically less than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Santiago to Calama.
Did you know?
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
Top travelled bus routes
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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting Santiago
Buses Leaving from Santiago
- Bus from Santiago to Puerto Montt
- Coach Santiago - Concepción
- Bus Santiago - Antofagasta
- Bus from Santiago to Mendoza
- Coach Santiago - La Serena
- Bus Santiago - Temuco
- Bus from Santiago to Los Alamos
- Coach Santiago - La Boca
- Bus Santiago - Licanray
- Bus from Santiago to Laraquete
- Coach Santiago - Carahue
- Bus Santiago - Quintero
- Bus from Santiago to Valparaiso
- Coach Santiago - Cholchol
- Bus Santiago - Coronel
Buses Going to Santiago
- Bus from Victoria to Santiago
- Coach Concepción - Santiago
- Bus Mendoza - Santiago
- Bus from Castro to Santiago
- Coach Valdivia - Santiago
- Bus Antofagasta - Santiago
- Bus from Labranza to Santiago
- Coach Pupuya - Santiago
- Bus La Boca - Santiago
- Bus from Alto Hospicio to Santiago
- Coach Vicuña - Santiago
- Bus Matanzas - Santiago
- Bus from Los Lagos to Santiago
- Coach Casablanca - Santiago
- Bus Purén - Santiago
Popular Buses Connecting Calama
Buses Leaving from Calama
- Bus from Calama to Iquique
- Coach Calama - La Serena
- Bus Calama - Antofagasta
- Bus from Calama to Sierra Gorda
- Coach Calama - Copiapo
- Bus Calama - Santiago
- Bus from Calama to Ovalle
- Coach Calama - Los Vilos
- Bus Calama - Vina del Mar
- Bus from Calama to Vallenar
- Coach Calama - Quillota
- Bus Calama - La Calera
- Bus from Calama to Baquedano
- Coach Calama - Pozo Almonte
- Bus Calama - Taltal
Buses Going to Calama
- Bus from Copiapo to Calama
- Coach Iquique - Calama
- Bus Uyuni - Calama
- Bus from Sierra Gorda to Calama
- Coach Coquimbo - Calama
- Bus Salta - Calama
- Bus from Valdivia to Calama
- Coach Quillota - Calama
- Bus Taltal - Calama
- Bus from Ovalle to Calama
- Coach Pozo Almonte - Calama
- Bus Osorno Province - Calama
- Bus from Baquedano to Calama
- Coach Puerto Montt - Calama
- Bus Alto Hospicio - Calama