Bus Tickets from Antofagasta to La Serena, CL

Next bus departures

Next departures for Antofagasta to La Serena on November 21
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Cikbus ElitéBus
Terminal Antofagasta
Terminal de Buses La SerenaCheapest
Pluss ChileBus
Terminal Antofagasta
Terminal de Buses La SerenaFastest
Cikbus ElitéBus
Terminal Antofagasta
Terminal de Buses La SerenaNo tags
Pluss ChileBus
Terminal Antofagasta
Terminal de Buses La SerenaNo tags
Pullman San AndrésBus
Terminal Carlos Oviedo Cavada
Terminal de Buses La SerenaNo tags

Last refresh of the prices: Yesterday at 11:22 AM -03.

Get from Antofagasta to La Serena

This route is served by bus only

The journey takes about 11 hours 30 minutes and with fares starting at just $21, it presents an excellent value for a comfortable ride.

22bus per day
11h 30mAverage Duration
438 milesDistance
18kgCO₂ emissions

Frequently asked questions about traveling from Antofagasta to La Serena, CL by bus

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/18
$29
11/19
$28
Today
$20
11/21
$20
11/22
$28
11/23
$28
11/24
$28
11/25
$28
busbud logoThe cheapest trip from Antofagasta to La Serena, CL was searched and found on Nov 20, 2025 with a price of $20

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Antofagasta to La Serena, CL, as early as possible.

You can expect to pay from $20 to $54 for a bus ticket from Antofagasta to La Serena, CL based on the last 2 days. You can expect to find the cheapest price for the trip at $20 which is on 2025-11-21.

Usually Pullman San Andres will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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