Bus Tickets from Calama to La Serena

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TodayMay 14
from $32
TomorrowMay 15
from $28
FriMay 16
from $28
SatMay 17
from $28
SunMay 18
MonMay 19
from $28
TueMay 20
from $28
WedMay 21

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 15 at
    Departure city: Calama
    Departure location: Calama
    Arrival time: May 16 at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: Cikbus ElitéCikbus Elité
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 15 at
    Departure city: Calama
    Departure location: Terminal de buses Calama
    Arrival time: May 16 at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: Cikbus ElitéCikbus Elité
    Vehicle: BusDuration:
  • Departure time: May 15 at
    Departure city: Calama
    Departure location: Terminal de buses Calama
    Arrival time: May 16 at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: Cikbus ElitéCikbus Elité
    Vehicle: BusDuration:
  • Departure time: May 15 at
    Departure city: Calama
    Departure location: Av. Balmaceda
    Arrival time: May 16 at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: Pluss ChilePluss Chile
    Vehicle: BusDuration:
  • Departure time: May 15 at
    Departure city: Calama
    Departure location: Calama
    Arrival time: May 16 at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: AndimarAndimar
    Vehicle: BusDuration:

Accepted payments

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Bus Calama to La Serena: Trip Overview

Average ticket price$40
Average bus trip duration15h
Number of daily buses27
Earliest bus departure8:30am
Distance534 miles (860 km)
Latest bus departure10:50pm

Calama to La Serena Bus

With Busbud, comparing and booking tickets for a bus from Calama to La Serena is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Calama to La Serena from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Calama to La Serena, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Calama - La Serena

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/12
$37
05/13
$40
Today
$32
05/15
$28
05/16
$28
05/17
$28
05/18
$32
05/19
$28
busbud logoThe cheapest trip from Calama to La Serena was searched and found on May 15, 2025 with a price of $28

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Calama to La Serena, as early as possible.

You can expect to pay from $28 to $48 for a bus ticket from Calama to La Serena based on the last 2 days. You can expect to find the cheapest price for the trip at $28 which is on 2025-05-15.

Usually PlussChile, Buses Andimar will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Calama to La Serena.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Calama to La Serena, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Calama to La Serena that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Calama to La Serena, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Calama by bus?

Bus from Calama to La Serena

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