Find coaches from Calama to La Serena, CL

Find affordable coach tickets from Calama to La Serena, CL with flexible options. Book your journey now

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Mon30 Jun
from US$28
Tue1 Jul
from US$33
Wed2 Jul
from US$33
Thu3 Jul
from US$33
Fri4 Jul
from US$33
Sat5 Jul
Sun6 Jul
Mon7 Jul

Cheap buses leaving Tuesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 1 July at
    Departure city: Calama
    Departure location: Calama
    Arrival time: 2 July at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: Cikbus ElitéCikbus Elité
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 1 July at
    Departure city: Calama
    Departure location: Terminal de buses Calama
    Arrival time: 1 July at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: Cikbus ElitéCikbus Elité
    Vehicle: BusDuration:
  • Departure time: 1 July at
    Departure city: Calama
    Departure location: Calama
    Arrival time: 2 July at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: Cikbus ElitéCikbus Elité
    Vehicle: BusDuration:
  • Departure time: 1 July at
    Departure city: Calama
    Departure location: Av. Balmaceda
    Arrival time: 2 July at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: Pluss ChilePluss Chile
    Vehicle: BusDuration:
  • Departure time: 1 July at
    Departure city: Calama
    Departure location: Calama
    Arrival time: 2 July at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: AndimarAndimar
    Vehicle: BusDuration:

Accepted payments

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Bus Calama to La Serena: Trip Overview

Average ticket priceUS$40
Average bus trip duration15h 5m
Number of daily buses25
Earliest bus departure08:30
Distance534 miles
Latest bus departure22:50

Calama to La Serena Bus

With Busbud, comparing and booking tickets for a bus from Calama to La Serena is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Calama to La Serena from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Calama to La Serena, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Calama - La Serena, CL

  1. What's the distance between Calama and La Serena by coach?

    The distance between Calama and La Serena by coach is approximately 534 miles (861 km).

  2. What is the best way to go from Calama to La Serena without flying?

    You have the option to select the coach for your journey on this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
26/06
US$31
27/06
US$38
Today
US$38
29/06
US$27
30/06
US$27
01/07
US$31
02/07
US$31
03/07
US$31
busbud logoThe cheapest trip from Calama to La Serena was searched and found on 29 Jun 2025 with a price of US$27

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Calama to La Serena as early as possible.

You can expect to pay from US$27 to US$48 for a bus ticket from Calama to La Serena based on the last 2 days. You can expect to find the cheapest price for the trip at US$27, which is on 2025-06-29.

Usually PlussChile will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Calama to La Serena.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Calama to La Serena, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Calama to La Serena that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Calama to La Serena, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Calama by bus?

Bus from Calama to La Serena

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