Based on 81 reviews, the company was rated 4 stars on Busbud. Travellers were especially satisfied with the departure location and the cleanliness but often complained with the Wi-Fi. Pluss Chile ticket prices on this trip start at £7
Based on 11379 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at £7
According to 12 reviews, Cikbus Elité received a 3.6-star rating for this journey. Travellers were especially satisfied with the staff and the seats, but some complained about the timeliness. Cikbus Elité ticket prices on this trip start at £8
Based on 54 reviews, the company was rated 4.2 stars on Busbud. Travellers were especially satisfied with the ticket access and the seats but often complained with the Wi-Fi. Buses Andimar ticket prices on this trip start at £11
Andimar La Serena Santiago recent customer reviews
Based on 52 reviews, the company was rated 3.8 stars on Busbud. Travellers were especially satisfied with the departure location and the ticket access but often complained with the Wi-Fi. Buses Romani ticket prices on this trip start at £2
Buses Romani La Serena Santiago recent customer reviews
Based on 13 reviews, the company was rated 3.6 stars on Busbud. Travellers were especially satisfied with the seats and the temperature but often complained with the timeliness. Pullman San Andres ticket prices on this trip start at £12
Based on 69 reviews, the company was rated 3 stars on Busbud. Travellers were especially satisfied with the timeliness and the departure location but often complained with the Wi-Fi. Buses Paravias ticket prices on this trip start at £10
Paravias La Serena Santiago recent customer reviews
I had selected an upstairs aisle seat and ended up in a cramped downstairs window seat. Uncomfortable and no place to put personal belongings.
Based on 12 reviews, Serena Mar was rated 4 stars for this trip. Serena Mar ticket prices on this trip start at £12, with the trip lasting on average 370.
Serena Mar La Serena Santiago recent customer reviews
A good way to travel this route is with Turisnorte buses. The company offers 1 daily departures, with ticket prices starting at £17 and the shortest trip taking about 435. Turisnorte gets you where you want to go for a fair price.
Based on 19 reviews, Condor Bus was rated 3.6 stars for this trip. Condor Bus ticket prices on this trip start at £12, with the trip lasting on average 397.
Based on 3 reviews, the company was rated 4.3 stars on Busbud. Travellers were especially satisfied with the staff and the timeliness but often complained with the Wi-Fi. Clikbus ticket prices on this trip start at £14
Panamericana Norte 208, La Serena, Región de Coquimbo, Chile
Stops in Santiago
A - San Borja
San Francisco de Borja 199-225, Santiago, Estación Central, Región Metropolitana, Chile
B - Terminal Sur
Santiago - Av Libertador Bernardo O'Higgins 3850, Santiago, Estación Central, Región Metropolitana, ChileTerminal Sur
C - Terminal Los Héroes
Tucapel Jiménez 21, 8340528 Santiago, Región Metropolitana, ChileTerminal Los Héroes
D - Terminal ETM
Pdte. Riesco 6391-6399, Las Condes, Región Metropolitana, ChileTerminal ETM
E - Pajaritos
Av. Gral. Oscar Bonilla 418, Lo Prado, Región Metropolitana, ChilePajaritos
F - Santiago
Juan Esteban Montero 5688, Las Condes, Las Condes, Región Metropolitana, Chile
Frequently asked questions about travelling by bus from La Serena, CL to Santiago, CL
How far is Santiago from La Serena by coach?
The distance between La Serena and Santiago by coach is approximately 247 miles (398 km).
Is there a way to reach Santiago from La Serena without a car?
The best way to go from La Serena to Santiago without a car is by coach. They are frequent and reliable, offering a convenient and eco-friendly journey. You can also consider rideshare services depending on your preferences.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
17/11
£9
18/11
£9
Today
£9
20/11
£7
21/11
£7
22/11
£7
23/11
£7
24/11
£7
The cheapest trip from La Serena, CL to Santiago, CL was searched and found on 24 Nov 2025 with a price of £7
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Serena, CL to Santiago, CL as early as possible.
You can expect to pay from £7 to £32 for a bus ticket from La Serena, CL to Santiago, CL based on the last 2 days. You can expect to find the cheapest price for the trip at £7, which is on 2025-11-24.
Usually Pluss Chile will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from La Serena, CL to Santiago, CL was searched and found on 24 Nov 2025 with a price of £7
