Based on 82 reviews, the company was rated 3.9 stars on Busbud. Travellers were especially satisfied with the departure location and the cleanliness but often complained with the WiFi. Pluss Chile ticket prices on this trip start at $15
Based on 11472 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. FlixBus ticket prices on this trip start at $13
According to 12 reviews, Cikbus Elité received a 3.6-star rating for this journey. Travellers were especially satisfied with the staff and the seats, but some complained about the timeliness. Cikbus Elité ticket prices on this trip start at $14
Based on 54 reviews, the company was rated 4.2 stars on Busbud. Travellers were especially satisfied with the ticket access and the seats but often complained with the WiFi. Buses Andimar ticket prices on this trip start at $20
Andimar La Serena Santiago recent customer reviews
Based on 13 reviews, the company was rated 3.6 stars on Busbud. Travellers were especially satisfied with the seats and the temperature but often complained with the timeliness. Pullman San Andres ticket prices on this trip start at $21
Based on 52 reviews, the company was rated 3.8 stars on Busbud. Travellers were especially satisfied with the departure location and the ticket access but often complained with the WiFi. Buses Romani ticket prices on this trip start at $14
Buses Romani La Serena Santiago recent customer reviews
Based on 70 reviews, the company was rated 3 stars on Busbud. Travellers were especially satisfied with the timeliness and the departure location but often complained with the WiFi. Buses Paravias ticket prices on this trip start at $17
Paravias La Serena Santiago recent customer reviews
I had selected an upstairs aisle seat and ended up in a cramped downstairs window seat. Uncomfortable and no place to put personal belongings.
Based on 12 reviews, Serena Mar was rated 4 stars for this trip. Serena Mar ticket prices on this trip start at $21, with the trip lasting on average 370.
Serena Mar La Serena Santiago recent customer reviews
A good way to travel this route is with Turisnorte buses. The company offers 1 daily departures, with ticket prices starting at $32 and the shortest trip taking about 435. Turisnorte gets you where you want to go for a fair price.
Based on 19 reviews, Condor Bus was rated 3.6 stars for this trip. Condor Bus ticket prices on this trip start at $22, with the trip lasting on average 397.
Based on 3 reviews, the company was rated 4.3 stars on Busbud. Travellers were especially satisfied with the staff and the timeliness but often complained with the WiFi. Clikbus ticket prices on this trip start at $25
Frequently asked questions about travelling from La Serena, CL to Santiago, CL by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from La Serena to Santiago?
The cheapest bus tickets from La Serena to Santiago start from $13. The average price for this route is around $28. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from La Serena to Santiago?
The average bus travel time from La Serena to Santiago is 6h 25m, covering a distance of 399 km. The quickest bus can get you there in 5h 10m and is operated by Clikbus.
Which bus companies service the La Serena to Santiago route?
What are the earliest and latest departure times for the bus from La Serena to Santiago?
The earliest bus departs from La Serena to Santiago at 12:05am. And the latest bus departs at 11:59pm.
What are the CO₂ emissions for the bus trip from La Serena to Santiago?
A bus trip from La Serena to Santiago generates an estimated 10 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from La Serena to Santiago?
According to Busbud customers, the highest-rated bus company on this route is Clikbus, with an average rating of 4.3 out of 5 stars based on 3 reviews.
Which bus company has the best Wi-Fi from La Serena to Santiago?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from La Serena to Santiago?
According to Busbud traveller reviews, the most punctual bus company on this route is Clikbus, with a punctuality rating of 5.0 out of 5 stars.
Which bus company has the cleanest buses from La Serena to Santiago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Pluss Chile, with a cleanliness rating of 4.6 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-27
$13
11-28
$33
Today
$17
11-30
$13
12-01
$13
12-02
$13
12-03
$13
12-04
$13
The cheapest trip from La Serena, CL to Santiago, CL was searched and found on Nov 27, 2025 with a price of $13
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Serena, CL to Santiago, CL, as early as possible.
You can expect to pay from $13 to $59 for a bus ticket from La Serena, CL to Santiago, CL based on the last 2 days. You can expect to find the cheapest price for the trip at $13 which is on 2025-12-01.
Usually Pluss Chile will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from La Serena, CL to Santiago, CL was searched and found on Nov 27, 2025 with a price of $13
