Based on 81 reviews, the company was rated 4 stars on Busbud. Travelers were especially satisfied with the departure location and the cleanliness but often complained with the wifi. Pluss Chile ticket prices on this trip start at $30
Based on 125 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the staff and the ticket access but often complained with the wifi. Cikbus Elité ticket prices on this trip start at $21
Cikbus Elité La Serena Antofagasta recent customer reviews
Very comfortable, pillows and blankets supplied, the evening meal was a bonus and staff were helpful! We slept the whole journey pretty much.
Based on 13 reviews, the company was rated 3.6 stars on Busbud. Travelers were especially satisfied with the seats and the temperature but often complained with the timeliness. Pullman San Andres ticket prices on this trip start at $35
Based on 54 reviews, the company was rated 4.2 stars on Busbud. Travelers were especially satisfied with the ticket access and the seats but often complained with the wifi. Buses Andimar ticket prices on this trip start at $28
Based on 52 reviews, the company was rated 3.8 stars on Busbud. Travelers were especially satisfied with the departure location and the ticket access but often complained with the wifi. Buses Romani ticket prices on this trip start at $33
Based on 19 reviews, Condor Bus was rated 3.6 stars for this trip. Condor Bus ticket prices on this trip start at $37, with the trip lasting on average 1038.
Based on 12 reviews, Serena Mar was rated 4 stars for this trip. Serena Mar ticket prices on this trip start at $42, with the trip lasting on average 887.
Based on 69 reviews, the company was rated 3 stars on Busbud. Travelers were especially satisfied with the timeliness and the departure location but often complained with the wifi. Buses Paravias ticket prices on this trip start at $64
Based on 3 reviews, the company was rated 4.3 stars on Busbud. Travelers were especially satisfied with the staff and the timeliness but often complained with the wifi. Clikbus ticket prices on this trip start at $27
Panamericana Norte 208, La Serena, Región de Coquimbo, Chile
Stops in Antofagasta
A - Terminal Antofagasta
TERMINAL ANTOFAGASTA, Av. Pedro Aguirre Cerda N° 5750, Antofagasta, ChileTerminal Antofagasta
B - Av. Pedro Aguirre Cerda, 253
Av. Pedro Aguirre Cerda 253, Antofagasta, Región de Antofagasta, Chile
C - Terminal Flota Barrios
Capitán Carlos Condell 2764, Antofagasta, Región de Antofagasta, Chile
D - Terminal Pullman Bus
Av. Pedro Aguirre Cerda 8729, Antofagasta, Región de Antofagasta, Chile
E - Terminal Buses Camus
Av. Radomiro Tomic 7421 , Antofagasta, Región de Antofagasta, Chile
F - Terminal Tur Bus
Almirante Juan José Latorre 2751, Antofagasta, Región de Antofagasta, Chile
Frequently asked questions about traveling from La Serena, CL to Antofagasta by bus
How far is La Serena from Antofagasta?
About 437 miles (704 km) separate La Serena and Antofagasta.
What are the departure and arrival stations when taking the bus from La Serena to Antofagasta?
Most of the buses traveling from La Serena to Antofagasta leave from Terminal de Buses La Serena and arrive at Terminal Antofagasta. These are the main pick-up and drop-off locations on this route, but you can also find other options that could better fit your plans.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/18
$29
11/19
$28
Today
$28
11/21
$20
11/22
$20
11/23
$20
11/24
$28
11/25
$28
The cheapest trip from La Serena, CL to Antofagasta was searched and found on Nov 23, 2025 with a price of $20
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Serena, CL to Antofagasta, as early as possible.
You can expect to pay from $20 to $54 for a bus ticket from La Serena, CL to Antofagasta based on the last 2 days. You can expect to find the cheapest price for the trip at $20 which is on 2025-11-23.
Usually Pluss Chile, Pullman San Andres will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.