Bus Tickets from La Serena, CL to Mendoza, AR

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TodayMay 25
from $88
TomorrowMay 26
from $48
TueMay 27
from $56
WedMay 28
ThuMay 29
from $48
FriMay 30
from $46
SatMay 31
SunJun 1

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 26 at
    Departure city: La Serena
    Departure location: Terminal de Buses La Serena
    Arrival time: May 27 at
    Destination city: Mendoza
    Destination location: Terminal De Omnibus Guaymallen
    Operated by: Buses Romani + CATA Internacional
    Buses Romani + CATA Internacional
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 26 at
    Departure city: La Serena
    Departure location: Terminal de Buses La Serena
    Arrival time: May 26 at
    Destination city: Mendoza
    Destination location: Terminal De Omnibus Guaymallen
    Operated by: Buses Romani + CATA Internacional
    Buses Romani + CATA Internacional
    Vehicle: BusDuration:
  • Departure time: May 26 at
    Departure city: La Serena
    Departure location: Terminal de Buses La Serena
    Arrival time: May 26 at
    Destination city: Mendoza
    Destination location: Terminal De Omnibus Guaymallen
    Operated by: Pluss Chile + CATA Internacional
    Pluss Chile + CATA Internacional
    Vehicle: BusDuration:
  • Departure time: May 26 at
    Departure city: La Serena
    Departure location: Terminal de Buses La Serena
    Arrival time: May 26 at
    Destination city: Mendoza
    Destination location: Terminal De Omnibus Guaymallen
    Operated by: Buses Romani + CATA Internacional
    Buses Romani + CATA Internacional
    Vehicle: BusDuration:
  • Departure time: May 26 at
    Departure city: La Serena
    Departure location: Terminal de Buses La Serena
    Arrival time: May 26 at
    Destination city: Mendoza
    Destination location: Terminal De Omnibus Guaymallen
    Operated by: Pluss Chile + CATA Internacional
    Pluss Chile + CATA Internacional
    Vehicle: BusDuration:

Accepted payments

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Bus La Serena to Mendoza: Trip Overview

Average ticket price$55
Average bus trip duration17h 15m
Number of daily buses8
Earliest bus departure1:10am
Distance251 miles (404 km)
Latest bus departure11:59pm

La Serena to Mendoza Bus

With Busbud, comparing and booking tickets for a bus from La Serena to Mendoza is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from La Serena to Mendoza.

Whether it is cheap bus tickets or more luxurious buses going to Mendoza from La Serena, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip La Serena, CL - Mendoza, AR

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/23
No data
05/24
No data
Today
$82
05/26
No data
05/27
No data
05/28
No data
05/29
No data
05/30
No data
busbud logoThe cheapest trip from La Serena to Mendoza was searched and found on May 25, 2025 with a price of $82

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Serena to Mendoza, as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from La Serena to Mendoza.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from La Serena to Mendoza.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from La Serena to Mendoza.

Make a music playlist for your bus ride from La Serena to Mendoza, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to La Serena by bus?

Bus from La Serena to Mendoza

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