Cheap buses leaving tomorrow
One passenger / one way
- This trip is recommended because it is the: Cheapest
- This trip is recommended because it is the: Fastest
Last refresh of the prices: Today at 3:57 PM -04.
Prices and availability are subject to change.
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Bus La Serena to Mendoza: Trip Overview
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La Serena to Mendoza Bus
With Busbud, comparing and booking tickets for a bus from La Serena to Mendoza is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from La Serena to Mendoza.
Whether it is cheap bus tickets or more luxurious buses going to Mendoza from La Serena, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in La Serena and Mendoza?
Frequently asked questions on the trip La Serena, CL - Mendoza, AR
What is the travel distance from La Serena to Mendoza?
It's about 405 km (251 miles) from La Serena to Mendoza.
What are the departure and arrival locations for buses traveling from La Serena to Mendoza?
Buses departing from Terminal de Buses La Serena in La Serena will take you to Mendoza Terminal in Mendoza.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from La Serena to Mendoza was searched and found on Jun 29, 2025 with a price of US$78To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Serena to Mendoza, as early as possible.
You can expect to pay from US$78 to US$91 for a bus ticket from La Serena to Mendoza based on the last 2 days. You can expect to find the cheapest price for the trip at US$78 which is on 2025-06-29.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from La Serena to Mendoza.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from La Serena to Mendoza.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from La Serena to Mendoza.
Make a music playlist for your bus ride from La Serena to Mendoza, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Top travelled bus routes
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Popular Buses Connecting La Serena
Buses Leaving from La Serena
- Bus from La Serena to Coquimbo
- Bus La Serena - Santiago
- La Serena - Antofagasta
- Bus from La Serena to Temuco
- Bus La Serena - Ovalle
- La Serena - Vallenar
- Bus from La Serena to Caldera
- Bus La Serena - Valparaiso
- La Serena - Baquedano
- Bus from La Serena to Vicuña
- Bus La Serena - Los Andes
- La Serena - Los Vilos
- Bus from La Serena to El Salvador
- Bus La Serena - Vina del Mar
- La Serena - La Calera
Buses Going to La Serena
- Bus from Santiago to La Serena
- Bus Ovalle - La Serena
- Copiapo - La Serena
- Bus from Temuco to La Serena
- Bus Arica - La Serena
- Valparaiso - La Serena
- Bus from Caldera to La Serena
- Bus Diego de Almagro - La Serena
- Pullalli - La Serena
- Bus from Los Vilos to La Serena
- Bus Baquedano - La Serena
- Coquimbo - La Serena
- Bus from Villarrica to La Serena
- Bus Antofagasta - La Serena
- Huasco - La Serena
Popular Buses Connecting Mendoza
Buses Leaving from Mendoza
- Bus from Mendoza to San Rafael
- Bus Mendoza - Las Leñas
- Mendoza - Las Cuevas
- Bus from Mendoza to Potrerillos
- Bus Mendoza - La Paz
- Mendoza - La Paz
- Bus from Mendoza to Salta
- Bus Mendoza - Córdoba
- Mendoza - Bariloche
- Bus from Mendoza to San Juan
- Bus Mendoza - Cacheuta Spa
- Mendoza - Resistencia
- Bus from Mendoza to General Roca
- Bus Mendoza - Villa Mercedes
- Mendoza - Merlo
Buses Going to Mendoza
- Bus from San Rafael to Mendoza
- Bus Cacheuta Spa - Mendoza
- Uspallata - Mendoza
- Bus from Las Heras to Mendoza
- Bus General Alvear - Mendoza
- Malargüe - Mendoza
- Bus from Pocito to Mendoza
- Bus Salta - Mendoza
- San Luis - Mendoza
- Bus from Jujuy to Mendoza
- Bus Liniers - Mendoza
- Villa Carlos Paz - Mendoza
- Bus from Santa Fe to Mendoza
- Bus El Talar de Pacheco - Mendoza
- Florencio Varela - Mendoza
Popular routes in this country
- Bus from Castro to Ancud
- Bus Santiago - Valparaiso
- Puerto Varas - Castro
- Bus from Calama to Santiago
- Bus Santiago - Vina del Mar
- Puerto Montt - Pucon
- Bus from Calama to Arica
- Bus Santiago - Pucon
- Puerto Natales - Estancia Pudeto
- Bus from Pucon to Santiago
- Bus Santiago - Temuco
- Ancud - Puerto Montt
- Bus from Temuco to Pucon
- Bus Calama - La Serena
- Santiago - Pichilemu