What is the distance between San Antonio and St. Louis?

About 793 miles (1278 km) separate San Antonio and St. Louis.

What are the departure and arrival stations when taking the bus from San Antonio to St. Louis?

If you're headed to St. Louis from San Antonio, chances are that your bus will leave from San Antonio Bus Station and arrive at Gateway Station. These are the main pick-up and drop-off locations on this route, but you can find others that could fit better into your travel plans.

What are the best sights and things to do in St. Louis?

Once in St. Louis, you can start exploring the city and discover its surroundings. The top sights and things to do are Scott Joplin House State Historic Site, Gateway Arch, Forest Park, St. Louis Cardinals and Lumière Place.

Bus San Antonio to St. Louis from $92 | Refundable Tickets

Next bus departures

Next departures for San Antonio to St. Louis on November 12
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Valley Transit + Greyhound Lines, Inc.	Bus	9:15pm	San Antonio Bus Station	1d 1h	10:50pm	Gateway Station	Cheapest
	Bus	12:40pm	San Antonio Bus Station	1d	12:55pm	Gateway Station	Fastest

Next departures for San Antonio to St. Louis on November 13
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	1:30am	San Antonio Bus Station	21h 20m	10:50pm	Gateway Station	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	7:30am	San Antonio Bus Station	23h 40m	7:10am	Gateway Station	No tags
	Bus	12:40pm	San Antonio Bus Station	1d	12:55pm	Gateway Station	No tags
Valley Transit + Greyhound Lines, Inc.	Bus	9:15pm	San Antonio Bus Station	1d 1h	10:50pm	Gateway Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	7:45am	Pearl District	23h 25m	7:10am	Gateway Station	No tags

Next departures for San Antonio to St. Louis on November 14
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	1:30am	San Antonio Bus Station	21h 20m	10:50pm	Gateway Station	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	7:30am	San Antonio Bus Station	23h 40m	7:10am	Gateway Station	No tags
	Bus	12:40pm	San Antonio Bus Station	1d	12:55pm	Gateway Station	No tags
Valley Transit + Greyhound Lines, Inc.	Bus	9:15pm	San Antonio Bus Station	1d 1h	10:50pm	Gateway Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	7:45am	Pearl District	23h 25m	7:10am	Gateway Station	No tags

Next departures for San Antonio to St. Louis on November 15
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	12:40pm	San Antonio Bus Station	1d	12:55pm	Gateway Station	Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	1:30am	San Antonio Bus Station	21h 20m	10:50pm	Gateway Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	7:30am	San Antonio Bus Station	23h 40m	7:10am	Gateway Station	No tags
Valley Transit + Greyhound Lines, Inc.	Bus	9:15pm	San Antonio Bus Station	1d 1h	10:50pm	Gateway Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	7:45am	Pearl District	23h 25m	7:10am	Gateway Station	No tags

Last refresh of the prices: Yesterday at 12:20 PM CST.

Compare 2 ways to go from San Antonio to St. Louis

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach St. Louis. The journey takes about 1 day, 42 minutes and with fares starting at just $112, it presents an excellent value for a comfortable ride.

1train per day

1d Average Duration

791 milesDistance

116kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$85 - $348	Average Duration1d 1h	CO₂ emissions 32kg CO₂e
Train	Average Price$112 - $333	Average Duration1d	CO₂ emissions 116kg CO₂e

Compare bus companies

Greyhound

3.5/587,369 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

Valley Transit

3/533 reviews

Staff3.8

Timeliness3.4

Cleanliness2.9

Wifi2.3

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in San Antonio and St. Louis?

Stops in San Antonio

A - San Antonio Bus Station

B - Tornado I-35

C - San Antonio, TX

D - 4407 S PanAm Expy #101

Stops in St. Louis

A - Gateway Station

Frequently asked questions about traveling from San Antonio, US to St. Louis by bus

What is the distance between San Antonio and St. Louis?
What are the departure and arrival stations when taking the bus from San Antonio to St. Louis?
What are the best sights and things to do in St. Louis?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/10

$176

11/11

$196

Today

$222

11/13

$220

11/14

$215

11/15

$147

11/16

$156

11/17

$92

The cheapest trip from San Antonio, US to St. Louis was searched and found on Nov 17, 2025 with a price of $92

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio, US to St. Louis, as early as possible.

You can expect to pay from $92 to $222 for a bus ticket from San Antonio, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $92 which is on 2025-11-17.