Bus from San Antonio, US to St. Louis: Tickets & Schedules
Next bus departures
Next departures for San Antonio to St. Louis on January 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Gateway Station
Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Saint Louis (Lambert Field)
Fastest
Next departures for San Antonio to St. Louis on January 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Gateway Station
Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Saint Louis (Lambert Field)
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Gateway Station
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Saint Louis (Lambert Field)
No tags
Bus
San Antonio Bus Station
Gateway Station
No tags
Next departures for San Antonio to St. Louis on January 29
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Gateway Station
Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Saint Louis (Lambert Field)
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Gateway Station
No tags
Bus
San Antonio Bus Station
Gateway Station
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Gateway Station
No tags
Next departures for San Antonio to St. Louis on January 30
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Gateway Station
Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Saint Louis (Lambert Field)
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Gateway Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Gateway Station
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Saint Louis (Lambert Field)
No tags
Next departures for San Antonio to St. Louis on January 31
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Gateway Station
Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Saint Louis (Lambert Field)
Fastest
Greyhound Lines Mexico + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Gateway Station
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
San Antonio Bus Station
Gateway Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Pearl District
Gateway Station
No tags
Last refresh of the prices: Yesterday at 3:29 PM CST.
Compare 2 ways to go from San Antonio to St. Louis
We recommend taking the bus
Among the sustainable travel choices, the Bus stands out as a good way to reach St. Louis. The journey takes about 23 hours 40 minutes and with fares starting at just $102, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Based on 39 reviews, the company was rated 3 stars on Busbud. Travelers were especially satisfied with the ticket access and the staff but often complained with the value for money. Valley Transit ticket prices on this trip start at $108
Frequently asked questions about traveling from San Antonio, US to St. Louis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from San Antonio to St. Louis?
The cheapest bus tickets from San Antonio to St. Louis start from $102. The average price for this route is around $155. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from San Antonio to St. Louis?
The average bus trip duration from San Antonio to St. Louis is 23h 40m, covering a distance of 792 miles (1277 km). The quickest bus can get you there in 1d and is operated by Greyhound.
Which bus companies service the San Antonio to St. Louis route?
Several major bus companies operate on this route with 6 buses available per day, including services from Greyhound, Valley Transit.
What is the earliest and latest departure time for the bus from San Antonio to St. Louis?
The earliest bus departs from San Antonio to St. Louis at 1:30am. And the latest bus departs at 9:15pm.
What are the CO₂ emissions for the bus trip from San Antonio to St. Louis?
A bus trip from San Antonio to St. Louis generates an estimated 32 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from San Antonio to St. Louis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87500 reviews.
Which bus company has the best Wi-Fi from San Antonio to St. Louis?
Based on reviews on Busbud, the bus company Valley Transit has the best Wi-Fi rating with a score of 2.8.
Which bus company has the most timely service from San Antonio to St. Louis?
According to Busbud traveler reviews, the most timely bus company on this route is Valley Transit, with a punctuality rating of 3.4 out of 5 stars.
Which bus company has the cleanest buses from San Antonio to St. Louis?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is Greyhound, with a cleanliness rating of 3.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
01/25
$182
01/26
$179
Today
$314
01/28
$148
01/29
$156
01/30
$195
01/31
$195
02/01
No data
The cheapest trip from San Antonio, US to St. Louis was searched and found on Jan 28, 2026 with a price of $148
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio, US to St. Louis, as early as possible.
You can expect to pay from $148 to $314 for a bus ticket from San Antonio, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $148 which is on 2026-01-28.
The cheapest trip from San Antonio, US to St. Louis was searched and found on Jan 28, 2026 with a price of $148
