What is the distance between San Antonio and St. Louis?

The distance covered from San Antonio to St. Louis is 1278 km (793 miles).

What are the departure and arrival locations for buses traveling from San Antonio to St. Louis?

Buses traveling this route start their trip at San Antonio Bus Station, in San Antonio, and end it at Gateway Station, in St. Louis.

Bus San Antonio to St. Louis from $133 | Refundable Tickets

Next bus departures

Next departures for San Antonio to St. Louis on November 12
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Valley Transit + Greyhound Lines, Inc.	Bus	9:15pm	San Antonio Bus Station	1d 1h	10:50pm	Gateway Station	Cheapest
	Bus	12:40pm	San Antonio Bus Station	1d	12:55pm	Gateway Station	Fastest

Next departures for San Antonio to St. Louis on November 13
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	1:30am	San Antonio Bus Station	21h 20m	10:50pm	Gateway Station	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	7:30am	San Antonio Bus Station	23h 40m	7:10am	Gateway Station	No tags
	Bus	12:40pm	San Antonio Bus Station	1d	12:55pm	Gateway Station	No tags
Valley Transit + Greyhound Lines, Inc.	Bus	9:15pm	San Antonio Bus Station	1d 1h	10:50pm	Gateway Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	7:45am	Pearl District	23h 25m	7:10am	Gateway Station	No tags

Next departures for San Antonio to St. Louis on November 14
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	1:30am	San Antonio Bus Station	21h 20m	10:50pm	Gateway Station	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	7:30am	San Antonio Bus Station	23h 40m	7:10am	Gateway Station	No tags
	Bus	12:40pm	San Antonio Bus Station	1d	12:55pm	Gateway Station	No tags
Valley Transit + Greyhound Lines, Inc.	Bus	9:15pm	San Antonio Bus Station	1d 1h	10:50pm	Gateway Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	7:45am	Pearl District	23h 25m	7:10am	Gateway Station	No tags

Next departures for San Antonio to St. Louis on November 15
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	12:40pm	San Antonio Bus Station	1d	12:55pm	Gateway Station	Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	1:30am	San Antonio Bus Station	21h 20m	10:50pm	Gateway Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	7:30am	San Antonio Bus Station	23h 40m	7:10am	Gateway Station	No tags
Valley Transit + Greyhound Lines, Inc.	Bus	9:15pm	San Antonio Bus Station	1d 1h	10:50pm	Gateway Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	7:45am	Pearl District	23h 25m	7:10am	Gateway Station	No tags

Last refresh of the prices: Yesterday at 12:20 PM CST.

Compare 2 ways to go from San Antonio to St. Louis

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach St. Louis. The journey takes about 1 day, 42 minutes, and with fares starting at just $161, it presents an excellent value for a comfortable ride.

1train per day

1d Average Duration

1276 kmDistance

116kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$122 - $499	Average Duration1d 1h	CO₂ emissions 32kg CO₂e
Train	Average Price$161 - $478	Average Duration1d	CO₂ emissions 116kg CO₂e

Compare bus companies

Greyhound

3.5/587,369 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Valley Transit

3/533 reviews

Staff3.8

Timeliness3.4

Cleanliness2.9

Wifi2.3

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in San Antonio and St. Louis?

Stops in San Antonio

A - San Antonio Bus Station

B - Tornado I-35

C - San Antonio, TX

D - 4407 S PanAm Expy #101

Stops in St. Louis

A - Gateway Station

Frequently asked questions about travelling from San Antonio, US to St. Louis by bus

What is the distance between San Antonio and St. Louis?
The distance covered from San Antonio to St. Louis is 1278 km (793 miles).
What are the departure and arrival locations for buses traveling from San Antonio to St. Louis?
Buses traveling this route start their trip at San Antonio Bus Station, in San Antonio, and end it at Gateway Station, in St. Louis.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-10

$253

11-11

$282

Today

$319

11-13

$317

11-14

$309

11-15

$212

11-16

$225

11-17

$133

The cheapest trip from San Antonio, US to St. Louis was searched and found on Nov 17, 2025 with a price of $133

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio, US to St. Louis, as early as possible.

You can expect to pay from $133 to $319 for a bus ticket from San Antonio, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $133 which is on 2025-11-17.