Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Valley Transit + Greyhound Lines, Inc. | Bus | San Antonio Bus Station | Gateway Station | Cheapest | ||||
Greyhound Lines Mexico + Greyhound Lines, Inc. | Bus | San Antonio Bus Station | Saint Louis (Lambert Field) | Fastest | ||||
Greyhound Lines Mexico + Greyhound Lines, Inc. | Bus | San Antonio Bus Station | Gateway Station | No tags | ||||
Valley Transit + Greyhound Lines, Inc. | Bus | San Antonio Bus Station | Saint Louis (Lambert Field) | No tags | ||||
 | Bus | San Antonio Bus Station | Gateway Station | No tags |
Last refresh of the prices: Yesterday at 12:21 PM CST.
Compare 2 ways to go from San Antonio to St. Louis
Among the sustainable travel choices, the Bus stands out as a good way to reach St. Louis. The journey takes about 23 hours 40 minutes, and with fares starting at just $142, it presents an excellent value for a comfortable ride.
Where are the popular stops in San Antonio and St. Louis?
Stops in San Antonio
- A500 N St Mary's St, San Antonio, TX 78205, USA
- B7914 Interstate 35 Access Rd, San Antonio, TX 78224, USA
- C4407 S PanAm Expy #101, San Antonio, TX 78225, USA
- D165 Bowie St, San Antonio, 78205
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Frequently asked questions about travelling from San Antonio, US to St. Louis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from San Antonio to St. Louis?
The cheapest bus tickets from San Antonio to St. Louis start from $142. The average price for this route is around $216. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from San Antonio to St. Louis?
The average bus travel time from San Antonio to St. Louis is 23h 40m, covering a distance of 1277 km. The quickest bus can get you there in 1d and is operated by Greyhound.
Which bus companies service the San Antonio to St. Louis route?
Several major bus companies operate on this route with 6 buses available per day, including services from Greyhound, Valley Transit.
What are the earliest and latest departure times for the bus from San Antonio to St. Louis?
The earliest bus departs from San Antonio to St. Louis at 1:30am. And the latest bus departs at 9:15pm.
What are the CO₂ emissions for the bus trip from San Antonio to St. Louis?
A bus trip from San Antonio to St. Louis generates an estimated 32 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from San Antonio to St. Louis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87500 reviews.
Which bus company has the best Wi-Fi from San Antonio to St. Louis?
Based on Busbud reviews, the bus company Valley Transit has the highest Wi-Fi rating with a score of 2.8.
Which bus company has the best on-time performance from San Antonio to St. Louis?
According to Busbud traveller reviews, the most punctual bus company on this route is Valley Transit, with a punctuality rating of 3.4 out of 5 stars.
Which bus company has the cleanest buses from San Antonio to St. Louis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Greyhound, with a cleanliness rating of 3.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Antonio, US to St. Louis was searched and found on Jan 28, 2026 with a price of $207To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio, US to St. Louis, as early as possible.
You can expect to pay from $207 to $439 for a bus ticket from San Antonio, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $207 which is on 2026-01-28.
