Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Memphis Bus Station | Des Moines | CheapestFastest |
Last refresh of the prices: Yesterday at 7:54 AM CST.
Get from Memphis to Des Moines
This route is served by bus only
The journey takes about 19 hours 55 minutes and with fares starting at just $134, it presents an excellent value for a comfortable ride.
1bus per day
19h 55mAverage Duration
493 milesDistance
20kgCO₂ emissions
Where are the popular stops in Memphis and Des Moines?
Stops in Des Moines
- A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314 - B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
Compare bus companies
3.5 out of 5 stars3.5/587,397 reviews
4 out of 5 stars4/5759 reviews
US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad
Frequently asked questions about traveling from Memphis, TN to Des Moines by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/24
No data
11/25
No data
Today
$130
11/27
No data
11/28
No data
11/29
No data
11/30
No data
12/01
No data
The cheapest trip from Memphis, TN to Des Moines was searched and found on Nov 26, 2025 with a price of $130To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Memphis, TN to Des Moines, as early as possible.
