Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Memphis Bus Station | Des Moines | CheapestFastest |
Last refresh of the prices: Yesterday at 7:54 AM CST.
Get from Memphis to Des Moines
This route is served by bus only
The journey takes about 19 hours 55 minutes, and with fares starting at just $193, it presents an excellent value for a comfortable ride.
1bus per day
19h 55mAverage Duration
795 kmDistance
20kgCO₂ emissions
Where are the popular stops in Memphis and Des Moines?
Stops in Des Moines
- A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314 - B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
Compare bus companies
3.5 out of 5 stars3.5/587,397 reviews
4 out of 5 stars4/5759 reviews
US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad
Frequently asked questions about travelling from Memphis, TN to Des Moines by bus
What is the distance between Memphis and Des Moines?
The distance between Memphis and Des Moines is approximately 783 km (485 miles).
What are the departure and arrival locations for buses traveling from Memphis to Des Moines?
Buses departing from Airways Transit Center in Memphis will take you to Jefferson/Trailways Depot in Des Moines.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-24
No data
11-25
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Today
$188
11-27
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11-28
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11-29
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11-30
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12-01
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The cheapest trip from Memphis, TN to Des Moines was searched and found on Nov 26, 2025 with a price of $188To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Memphis, TN to Des Moines, as early as possible.
