Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 11158 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the ticket access and the staff but often complained with the wifi. BlaBlaCar Bus ticket prices on this trip start at $61
Based on 1057 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the departure location and the value for money but often complained with the wifi. RegioJet ticket prices on this trip start at $62
Frequently asked questions about traveling from Lyon to Prague by bus
What is the distance between Lyon and Prague?
Lyon and Prague are 534 miles (861 km) apart.
What are the departure and arrival stations when taking the bus from Lyon to Prague?
If you're headed to Prague from Lyon, chances are that your bus will depart from Perrache and arrive at Florenc. These are the main departure and arrival locations on this route, but you can also find other options that could better fit your plans.
What are the best sights and things to do in Prague?
Once in Prague, you can start exploring the city and discover its surroundings. The top sights and things to do are Mind Maze, KGB Museum, Prague Castle and St. Vitus’ Cathedral, Karlův most (Charles Bridge) and Prague Shooting Trips.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/23
No data
11/24
$95
Today
No data
11/26
$67
11/27
No data
11/28
$82
11/29
$72
11/30
$60
The cheapest trip from Lyon to Prague was searched and found on Nov 30, 2025 with a price of $60
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Prague, as early as possible.
You can expect to pay from $60 to $100 for a bus ticket from Lyon to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $60 which is on 2025-11-30.
The cheapest trip from Lyon to Prague was searched and found on Nov 30, 2025 with a price of $60
