Bus from Lyon to Prague: Tickets & Schedules

Next bus departures

Next departures for Lyon to Prague on November 28
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
BlaBlaCar BusBus
    		Lyon - Perrache Bus Station
    		FlorencCheapestFastest

    Last refresh of the prices: Yesterday at 8:14 AM CET.

    Get from Lyon to Prague

    This route is served by bus only

    The journey takes about 19 hours 5 minutes, and with fares starting at just $83, it presents an excellent value for a comfortable ride.

    7bus per day
    19h 5mAverage Duration
    863 kmDistance
    22kgCO₂ emissions

    Frequently asked questions about travelling from Lyon to Prague by bus

    1. What is the distance between Lyon and Prague?

      It's about 861 km (534 miles) from Lyon to Prague.

    2. What are the departure and arrival locations for buses traveling from Lyon to Prague?

      Buses departing from Perrache in Lyon will take you to Florenc in Prague.

    Find cheapest prices for buses

    Price is for a one-way ticket for one passenger and based on past searches.

    Best price found
    11-24
    $137
    11-25
    No data
    Today
    $96
    11-27
    No data
    11-28
    $130
    11-29
    $104
    11-30
    $86
    12-01
    $81
    busbud logoThe cheapest trip from Lyon to Prague was searched and found on Dec 1, 2025 with a price of $81

    To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Prague, as early as possible.

    You can expect to pay from $81 to $143 for a bus ticket from Lyon to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $81 which is on 2025-12-01.

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