Bus Tickets from Lyon to Prague

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TomorrowJul 28
TueJul 29
from US$78
WedJul 30
from US$93
ThuJul 31
FriAug 1
SatAug 2
from US$86
SunAug 3
MonAug 4

Cheap buses leaving Tuesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: July 29 at
    Departure city: Lyon
    Departure location: Lyon - Perrache Bus Station
    Arrival time: July 29 at
    Destination city: Prague
    Destination location: Florenc
    Operated by: BlaBlaCar BusBlaBlaCar Bus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: July 29 at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: July 30 at
    Destination city: Prague
    Destination location: Prague (Na Knížecí)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: July 29 at
    Departure city: Lyon
    Departure location: Lyon - Perrache Bus Station
    Arrival time: July 30 at
    Destination city: Prague
    Destination location: Florenc
    Operated by: BlaBlaCar BusBlaBlaCar Bus
    Vehicle: BusDuration:
  • Departure time: July 29 at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: July 29 at
    Destination city: Prague
    Destination location: Prague (Central Bus Station Florenc)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: July 29 at
    Departure city: Lyon
    Departure location: Aéroport LYS
    Arrival time: July 30 at
    Destination city: Prague
    Destination location: Florenc
    Operated by: BlaBlaCar BusBlaBlaCar Bus
    Vehicle: BusDuration:

Last refresh of the prices: Last Tuesday at 9:37 PM CEST.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Lyon to Prague: Trip Overview

Average Ticket PriceUS$89
Average Bus Trip Duration18h 10m
Number of daily buses7
Earliest bus departure1:20am
Distance853 km
Latest bus departure10:00pm

Lyon to Prague Bus

With Busbud, comparing and booking tickets for a bus from Lyon to Prague is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Lyon to Prague from the most reliable bus companies operating this trip.

Discover how much the bus trip from Lyon to Prague will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Lyon - Prague

  1. What is the distance between Lyon and Prague?

    It's about 861 km (534 miles) from Lyon to Prague.

  2. What are the departure and arrival locations for buses traveling from Lyon to Prague?

    Buses departing from Perrache in Lyon will take you to Florenc in Prague.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07-25
US$64
07-26
US$85
Today
US$94
07-28
US$73
07-29
US$73
07-30
US$90
07-31
US$71
08-01
US$72
busbud logoThe cheapest trip from Lyon to Prague was searched and found on Jul 25, 2025 with a price of US$64

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Prague, as early as possible.

You can expect to pay from US$64 to US$200 for a bus ticket from Lyon to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at US$71 which is on 2025-07-31.

Usually Flixbus (FR) will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Lyon to Prague.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Lyon to Prague, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Lyon to Prague will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Lyon to Prague, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Lyon by bus?

Bus from Lyon to Prague

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Popular bus departures from Lyon

Popular bus departures to Lyon

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