Among the sustainable travel choices, the bus stands out as the good way to reach Brno. The journey takes about 2 hours 40 minutes and with fares starting at just $11, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 1057 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the departure location and the value for money but often complained with the wifi. RegioJet ticket prices on this trip start at $13
Gepard Express offers 6 daily departures, and you can find tickets starting at $28. The quickest ride takes around 147. Gepard Express offers a cost-effective solution to get you where you need to be.
Based on 20 reviews, the company was rated 4.5 stars on Busbud. Travelers were especially satisfied with the staff and the timeliness but often complained with the power outlets. IC Bus ticket prices on this trip start at $15
Based on 149 reviews, the company was rated 4.5 stars on Busbud. Travelers were especially satisfied with the temperature and the seats but often complained with the wifi. Slovak Lines ticket prices on this trip start at $18
A-Express offers 1 daily buses from Prague to Brno. Though the average price for this trip is $20, you can find tickets starting at $20. The trip between the two cities usually takes about 155.
Musil Tour offers 1 daily departures, and you can find tickets starting at $15. The quickest ride takes around 150. Musil Tour offers a cost-effective solution to get you where you need to be.
Based on 2 reviews, Avtokombinat-1 OOO was rated 3 stars for this trip. Avtokombinat-1 OOO ticket prices on this trip start at $19, with the trip lasting on average 190.
A good way to travel this route is with Maksymiuk FOP buses. The company offers 1 daily departures, with ticket prices starting at $15 and the shortest trip taking about 120. Maksymiuk FOP gets you where you want to go for a fair price.
Monobus offers 1 daily departures, and you can find tickets starting at $16. The quickest ride takes around 200. Monobus offers a cost-effective solution to get you where you need to be.
Based on 490 reviews, the company was rated 3.9 stars on Busbud. Travelers were especially satisfied with the cleanliness and the ticket access but often complained with the power outlets. Infobus ticket prices on this trip start at $13
Frequently asked questions about traveling from Prague to Brno by bus
What is the distance between Prague and Brno?
The distance separating Prague and Brno is 116 miles (187 km).
What are the departure and arrival stations when taking the bus from Prague to Brno?
If you're headed to Brno from Prague, chances are that your bus will leave from Florenc and arrive at ÚAN Zvonařka. These are the most popular pick-up and drop-off locations on this route, but you could find others that could be a better fit for your travel plans.
What are the best sights and things to do in Brno?
Once in Brno, you can start exploring the city and discover its surroundings. The top sights and things to do are Veveří Castle, The Cathedral Of St. Peter And Paul, BrainFAQ, Zoo Brno and Seg Agency.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/16
$16
11/17
$15
Today
$9
11/19
$7
11/20
$7
11/21
$7
11/22
$7
11/23
$9
The cheapest trip from Prague to Brno was searched and found on Nov 19, 2025 with a price of $7
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Brno, as early as possible.
You can expect to pay from $7 to $31 for a bus ticket from Prague to Brno based on the last 2 days. You can expect to find the cheapest price for the trip at $7 which is on 2025-11-19.
What's the cheapest way to go from Prague to Brno?
The bus is the cheapest travel choice for this destination
The cheapest trip from Prague to Brno was searched and found on Nov 19, 2025 with a price of $7
The bus is the cheapest travel choice for this destination
