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- This trip is recommended because it is: Cheapest + FastestDeparture time: June 18 atDeparture city: KnoxvilleDeparture location: Knoxville Bus StationArrival time: June 19 atDestination city: ColumbusDestination location: Columbus (E Mound St)Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration:
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Bus Knoxville to Columbus: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Knoxville Columbus recent customer reviews
Its honestly really scary and id never do it again as a young girl alone
Elle R.
Knoxville to Columbus Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Knoxville to Columbus.
Bus service from Knoxville to Columbus will be provided by the most trusted bus companies.
Discover how much the bus trip from Knoxville to Columbus will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Knoxville and Columbus?
Frequently asked questions for your trip Knoxville (TN) - Columbus (OH)
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Knoxville to Columbus was searched and found on Jun 12, 2025 with a price of $64To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville to Columbus, as early as possible.
You can expect to pay from $64 to $82 for a bus ticket from Knoxville to Columbus based on the last 2 days. You can expect to find the cheapest price for the trip at $77 which is on 2025-06-15.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Knoxville to Columbus but it'll also be endearing to native speakers who will surely appreciate your effort.
Much more than a mere vehicle taking you from Knoxville to Columbus, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Knoxville to Columbus will emit less CO2 than a car or an airplane.
Make a music playlist for your bus ride from Knoxville to Columbus, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
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Popular Buses Connecting Knoxville
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Popular Buses Connecting Columbus
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Buses Going to Columbus
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