Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Kansas City Bus Station | Tupelo (Brothers Quick Stop) | No tags | ||||
| Bus | Kansas City Bus Station | Tupelo (Brothers Quick Stop) | No tags | ||||
| Bus | Kansas City Bus Station | Tupelo (Brothers Quick Stop) | No tags | ||||
FlixBus + Greyhound | Bus | Kansas City Bus Station | Tupelo (Brothers Quick Stop) | No tags | ||||
| Bus | Kansas City Bus Station | Tupelo (Brothers Quick Stop) | No tags |
Get from Kansas City to Tupelo
The journey takes about 15 hours 50 minutes and with fares starting at just $178, it presents an excellent value for a comfortable ride.
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Kansas City, MO to Tupelo by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Kansas City to Tupelo?
The cheapest bus tickets from Kansas City to Tupelo start from $178. The average price for this route is around $178. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Kansas City to Tupelo?
The average bus trip duration from Kansas City to Tupelo is 15h 50m, covering a distance of 467 miles (754 km). The quickest bus can get you there in 15h 50m and is operated by Greyhound.
Which bus companies service the Kansas City to Tupelo route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Kansas City to Tupelo?
The earliest bus departs from Kansas City to Tupelo at 6:50pm. And the latest bus departs at 6:50pm.
What are the CO₂ emissions for the bus trip from Kansas City to Tupelo?
A bus trip from Kansas City to Tupelo generates an estimated 19 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Kansas City, MO to Tupelo was searched and found on Jan 21, 2026 with a price of $187To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Kansas City, MO to Tupelo, as early as possible.
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