Bus Tickets from Detroit, MI to Tupelo

Previously seen trips

Next departures for Detroit to Tupelo on November 4
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
    		Detroit Bus Station
    		Tupelo (Brothers Quick Stop)No tags
    Greyhound
      		Detroit Bus Station
      		Tupelo (Brothers Quick Stop)No tags
      Greyhound
        		Detroit Bus Station
        		Tupelo (Brothers Quick Stop)No tags
        Greyhound
          		Detroit Bus Station
          		Tupelo (Brothers Quick Stop)No tags
          Greyhound
            		Detroit Bus Station
            		Tupelo (Brothers Quick Stop)No tags

            Accepted payments

            • Visa
            • MasterCard
            • American Express
            • China Union Pay
            • Diners Club Canada
            • Discover Click to Pay
            • JCB payment
            • Klarna (Pay over time)
            • Google Pay

            Get from Detroit to Tupelo

            This route is served by bus only

            The journey takes about 1 day, 40 minutes and with fares starting at just $92, it presents an excellent value for a comfortable ride.

            4bus per day
            1d Average Duration
            636 milesDistance
            26kgCO₂ emissions

            Bus Detroit, MI to Tupelo: Trip Overview

            Average ticket price$141
            Average bus trip duration1d
            Number of daily buses4
            Earliest bus departure6:40am
            Distance636 miles (1025 km)
            Latest bus departure11:25pm

            Detroit to Tupelo Bus

            With Busbud, comparing and booking tickets for a bus from Detroit to Tupelo is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

            We make sure you can find a bus service from Detroit to Tupelo from the most reliable bus companies operating this trip.

            Whether it is cheap bus tickets or more luxurious buses going to Tupelo from Detroit, we help you find what you're looking for based on how much of a budget you have.

            Frequently asked questions for your trip Detroit, MI - Tupelo

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            11/02
            $168
            11/03
            $122
            Today
            $124
            11/05
            No data
            11/06
            No data
            11/07
            No data
            11/08
            No data
            11/09
            No data
            busbud logoThe cheapest trip from Detroit, MI to Tupelo was searched and found on Nov 3, 2025 with a price of $122

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Tupelo, as early as possible.

            About Bus Travel

            Bus Travel Tips

            Meet and talk to locals at the bus stations while traveling from Detroit to Tupelo.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

            Start sightseeing the minute your bus leaves the station. If you're on the night bus from Detroit to Tupelo, get comfy and count the stars.

            Buses are energy-efficient. Carrying a passenger over 100 kms by bus only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Detroit to Tupelo.

            Make a music playlist for your bus ride from Detroit to Tupelo, and enjoy the scenery to tunes from your own personal soundtrack.

            Did you know?

            One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

            It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

            The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

            Will you be returning to Detroit, MI by bus?

            Bus from Tupelo to Detroit, MI

            Why choose Busbud?

            The Best Way To Book Bus and Train Tickets

            Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

            People from around the world trust Busbud

            ‌

            Popular Buses Connecting Detroit

            Buses Leaving from Detroit

            Buses Going to Detroit

            Popular Buses Connecting Tupelo

            Buses Leaving from Tupelo

            Buses Going to Tupelo