Bus from Detroit, MI to Tupelo: Tickets & Schedules

Next bus departures

Next departures for Detroit to Tupelo on December 25
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.Bus
Detroit Bus Station
Tupelo (Brothers Quick Stop)CheapestFastest
Greyhound Lines, Inc.Bus
Detroit Bus Station
Tupelo (Brothers Quick Stop)No tags
Greyhound Lines, Inc. + FlixBus
Bus
Detroit Bus Station
Tupelo (Brothers Quick Stop)No tags
Greyhound Lines, Inc.Bus
Detroit Bus Station
Tupelo (Brothers Quick Stop)No tags

Last refresh of the prices: Yesterday at 1:16 AM EST.

Get from Detroit to Tupelo

This route is served by bus only

The journey takes about 1 day, 40 minutes, and with fares starting at just $187, it presents an excellent value for a comfortable ride.

4bus per day
1d Average Duration
1025 kmDistance
26kgCO₂ emissions

Frequently asked questions about travelling from Detroit, MI to Tupelo by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Detroit to Tupelo?

    The cheapest bus tickets from Detroit to Tupelo start from $187. The average price for this route is around $246. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Detroit to Tupelo?

    The average bus travel time from Detroit to Tupelo is 1d , covering a distance of 1025 km. The quickest bus can get you there in 19h 20m and is operated by Greyhound.

  3. Which bus companies service the Detroit to Tupelo route?

    Several major bus companies operate on this route with 4 buses available per day.

  4. What are the earliest and latest departure times for the bus from Detroit to Tupelo?

    The earliest bus departs from Detroit to Tupelo at 6:40am. And the latest bus departs at 11:25pm.

  5. What are the CO₂ emissions for the bus trip from Detroit to Tupelo?

    A bus trip from Detroit to Tupelo generates an estimated 26 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
12-22
$369
12-23
$340
Today
$306
12-25
$200
12-26
$242
12-27
$245
12-28
$334
12-29
$292
busbud logoThe cheapest trip from Detroit, MI to Tupelo was searched and found on Dec 25, 2025 with a price of $200

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Tupelo, as early as possible.

You can expect to pay from $200 to $444 for a bus ticket from Detroit, MI to Tupelo based on the last 2 days. You can expect to find the cheapest price for the trip at $200 which is on 2025-12-25.

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