What is the travel distance from Boston to Florence?

The distance separating Boston and Florence is 729 miles (1176 km).

What are the departure and arrival stations when taking the bus from Boston to Florence?

The majority of buses traveling from Boston to Florence start their journey at Back Bay Station and wind up at Florence Bus Station. These are the most popular departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.

What are the best sights and things to do in Florence?

Once in Florence, you can start exploring the city and discover its surroundings. The top sights and things to do are Galleria dell’Accademia, Museo Galileo - Institute and Museum of the History of Science, Museo degli Innocenti, Palazzo Vecchio and Galleria degli Uffizi.

Bus Boston to Florence from $79 | Refundable Tickets

Previously seen trips

Next departures for Boston to Florence on November 25
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound + FlixBus	Bus	1:45pm	151 Steel Pl, Cambridge	23h	12:45pm	Bus station	No tags
	Bus	4:45pm	Boston (South Station)	20h	12:45pm	Bus station	No tags
Greyhound + FlixBus	Bus	1:45pm	151 Steel Pl, Cambridge	23h	12:45pm	Bus station	No tags
FlixBus + Greyhound	Bus	1:45pm	151 Steel Pl, Cambridge	23h	12:45pm	Bus station	No tags
Greyhound + FlixBus	Bus	5:15pm	Boston (South Station)	19h 30m	12:45pm	Bus station	No tags

Compare 2 ways to go from Boston to Florence

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Florence. The journey takes about 18 hours and with fares starting at just $121, it presents an excellent value for a comfortable ride.

9train per day

18hAverage Duration

733 milesDistance

108kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$86 - $325	Average Duration1d 4h	CO₂ emissions 30kg CO₂e
Train	Average Price$121 - $814	Average Duration18h	CO₂ emissions 108kg CO₂e

Where are the popular stops in Boston and Florence?

Stops in Boston

A
Back Bay Station
145 Dartmouth St, Boston, MA 02116, USA
Visit page
B
North Station
100 Legends Way, Boston, MA 02114, USA
Visit page
C
South Station
700 Atlantic Ave, Boston, MA 02205, USA
Visit page
D
Copley Square
115-127 St James Ave, Boston, MA 02116, USA
E
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA
F
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Compare bus companies

FlixBus

3.5/511,440 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,394 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Boston, MA, US to Florence, SC, US by bus

What is the travel distance from Boston to Florence?
What are the departure and arrival stations when taking the bus from Boston to Florence?
What are the best sights and things to do in Florence?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/23

$158

11/24

$175

Today

$234

11/26

$189

11/27

$133

11/28

No data

11/29

$185

11/30

$244

The cheapest trip from Boston, MA, US to Florence, SC, US was searched and found on Nov 27, 2025 with a price of $133

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Florence, SC, US, as early as possible.

You can expect to pay from $133 to $317 for a bus ticket from Boston, MA, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $133 which is on 2025-11-27.

Usually FlixBus, Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.