What is the travel distance from Boston to Florence?

It's about 1176 km (729 miles) from Boston to Florence.

What are the departure and arrival locations for buses traveling from Boston to Florence?

Buses traveling this route start their trip at Back Bay Station, in Boston, and end it at Florence Bus Station, in Florence.

Bus Boston to Florence from $114 | Refundable Tickets

Previously seen trips

Next departures for Boston to Florence on November 19
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound	Bus	9:45am	Boston (South Station)	19h 50m	5:35am	Florence, SC	No tags
	Bus	9:00am	Boston (South Station)	20h 35m	5:35am	Florence, SC	No tags
	Bus	10:45am	151 Steel Pl, Cambridge	1d 13h	11:59pm	Florence, SC	No tags
FlixBus + Greyhound	Bus	1:45pm	151 Steel Pl, Cambridge	23h	12:45pm	Bus station	No tags
	Bus	5:15pm	Boston (South Station)	19h 30m	12:45pm	Bus station	No tags

Compare 2 ways to go from Boston to Florence

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Florence. The journey takes about 18 hours, and with fares starting at just $174, it presents an excellent value for a comfortable ride.

10train per day

18hAverage Duration

1182 kmDistance

108kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$124 - $468	Average Duration1d 4h	CO₂ emissions 30kg CO₂e
Train	Average Price$174 - $1,173	Average Duration18h	CO₂ emissions 108kg CO₂e

Compare bus companies

FlixBus

3.5/511,380 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Greyhound

3.5/587,382 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Boston and Florence?

Stops in Boston

A - Back Bay Station

B - North Station

C - South Station

D - Copley Square

E - Prudential MBTA Station

F - Copley MBTA Station

Stops in Florence

A - Florence Bus Station

B - TA Travel Center - Florence

Frequently asked questions about travelling from Boston, MA, US to Florence, SC, US by bus

What is the travel distance from Boston to Florence?
It's about 1176 km (729 miles) from Boston to Florence.
What are the departure and arrival locations for buses traveling from Boston to Florence?
Buses traveling this route start their trip at Back Bay Station, in Boston, and end it at Florence Bus Station, in Florence.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-17

$127

11-18

$151

Today

$185

11-20

$181

11-21

$224

11-22

No data

11-23

No data

11-24

$253

The cheapest trip from Boston, MA, US to Florence, SC, US was searched and found on Nov 17, 2025 with a price of $127

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Florence, SC, US, as early as possible.

You can expect to pay from $127 to $281 for a bus ticket from Boston, MA, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $181 which is on 2025-11-20.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.