Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Brookline | Florence, SC | Cheapest | |||||
 | Boston (South Station) | Bus station | Fastest | |||||
Greyhound Lines, Inc. + FlixBus | Boston (South Station) | Florence, SC | No tags | |||||
 | Brookline | Florence, SC | No tags | |||||
FlixBus + Greyhound Lines, Inc. | Boston (South Station) | Florence, SC | No tags |
Last refresh of the prices: Today at 6:11 PM EST.
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Compare 2 ways to travel from Boston to Florence
Among the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 1 day, 1 hour 45 minutes and with fares starting at just R 1 354, it presents an excellent value for a comfortable ride.
Bus Boston, MA, US to Florence, SC, US: Trip Overview
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Boston to Florence Bus
With Busbud, comparing and booking tickets for a bus from Boston to Florence is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Boston to Florence.
Whether it is cheap bus tickets or more luxurious buses going to Florence from Boston, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Boston and Florence?
Frequently asked questions on the trip Boston, MA, US - Florence, SC, US
How much does a bus ticket from Boston to Florence cost?
The bus ticket price from Boston to Florence starts at R 1 354. The best way to find cheap bus tickets from Boston to Florence is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Boston to Florence?
The average travel time between Boston and Florence is around 1d 1h, although the fastest bus will take about 19h 30m. This is the time it takes to travel the 1176 km that separates the two cities.
How many daily bus connections are there between Boston and Florence?
The number of buses from Boston to Florence can differ depending on the day of the week. On average, there are 4 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Boston to Florence by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Boston to Florence?
When taking the bus from Boston to Florence, you can travel comfortably and safely with FlixBus, Greyhound.
What are the departure and arrival stations when taking the bus from Boston to Florence?
Buses travelling between Boston and Florence leave from Back Bay Station or South Station and arrive at Florence Bus Station, TA Travel Center - Florence.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Boston, MA, US to Florence, SC, US was searched and found on 07 Nov 2025 with a price of R 1 493To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Florence, SC, US as early as possible.
You can expect to pay from R 1 493 to R 2 729 for a bus ticket from Boston, MA, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 493, which is on 2025-11-07.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Boston to Florence.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Boston to Florence.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Boston to Florence.
Make a music playlist for your bus ride from Boston to Florence, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
What's the cheapest way to go from Boston, MA, US to Florence, SC, US?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting Boston
Buses Leaving from Boston
- Bus from Boston to Chicago
- Coach Boston - Philadelphia
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- Bus from Boston to London
- Coach Boston - Portland
- Bus Boston - Toronto
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- Coach Boston - Frisco
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Buses Going to Boston
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- Coach Manchester - Boston
- Bus Lenox - Boston
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- Bus Philadelphia - Boston
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- Coach Lansing - Boston
- Bus Provincetown - Boston
- Bus from Canton to Boston
- Coach Beckley - Boston
- Bus Benson - Boston
- Bus from Albany to Boston
- Coach Lumberton - Boston
- Bus Pittsfield - Boston
Popular Buses Connecting Florence
Buses Leaving from Florence
- Bus from Florence to Kansas City
- Coach Florence - Kansas City
- Bus Florence - Oklahoma City
- Bus from Florence to Houston
- Coach Florence - Jackson
- Bus Florence - Jackson
- Bus from Florence to Tyrone
- Coach Florence - Dallas
- Bus Florence - Lansing
- Bus from Florence to Nashville
- Coach Florence - Statesboro
- Bus Florence - Norcross
- Bus from Florence to Macon
- Coach Florence - Elyria
- Bus Florence - Rochester
Buses Going to Florence
- Bus from Syracuse to Florence
- Coach Manchester - Florence
- Bus Columbus - Florence
- Bus from Columbus to Florence
- Coach Los Angeles - Florence
- Bus Toronto - Florence
- Bus from Albuquerque to Florence
- Coach Buffalo - Florence
- Bus Fort Lauderdale - Florence
- Bus from Killeen to Florence
- Coach Binghamton - Florence
- Bus St. Louis - Florence
- Bus from Denver to Florence
- Coach Portland - Florence
- Bus Stamford - Florence
Popular routes in this country
- Bus from Buffalo to Niagara Falls
- Coach Houston - Brownsville
- Bus New York City - Fleischmanns
- Bus from Newark to Norfolk
- Coach Milwaukee - Appleton
- Bus Hartford - New York City
- Bus from New York City to Pittsburgh
- Coach Rancho Cucamonga - Los Angeles
- Bus Harrisonburg - Blacksburg
- Bus from Norfolk to Newark
- Coach Alexandria - Charlottesville