Bus from Florence, SC, US to Boston, MA, US: Tickets & Schedules

Previously seen trips

Next departures for Florence to Boston on November 28
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
GreyhoundBus
Bus station
Boston (South Station)No tags
FlixBus + Greyhound
Bus
Bus station
151 Steel Pl, CambridgeNo tags
Greyhound + FlixBus
Bus
Bus station
151 Steel Pl, CambridgeNo tags
GreyhoundBus
Bus station
Boston (South Station)No tags
GreyhoundBus
Bus station
Boston (South Station)No tags

Compare 2 ways to go from Florence to Boston

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Boston. The journey takes about 19 hours 32 minutes and with fares starting at just $142, it presents an excellent value for a comfortable ride.

5train per day
19h 32mAverage Duration
723 milesDistance
106kgCO₂ emissions
Average Price$101 - $545Average Duration1d 2h
30kg CO₂e
Average Price$142 - $663Average Duration19h 32m
106kg CO₂e

Frequently asked questions about traveling from Florence, SC, US to Boston, MA, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Florence to Boston?

    The cheapest bus tickets from Florence to Boston start from $101. The average price for this route is around $154. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Florence to Boston?

    The average bus trip duration from Florence to Boston is 1d 2h, covering a distance of 733 miles (1182 km). The quickest bus can get you there in 22h 5m and is operated by Greyhound.

  3. Which bus companies service the Florence to Boston route?

    Several major bus companies operate on this route with 4 buses available per day, including services from FlixBus, Greyhound.

  4. What is the earliest and latest departure time for the bus from Florence to Boston?

    The earliest bus departs from Florence to Boston at 12:05am. And the latest bus departs at 4:30pm.

  5. What are the CO₂ emissions for the bus trip from Florence to Boston?

    A bus trip from Florence to Boston generates an estimated 30 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Florence to Boston?

    According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.

  7. Which bus company has the best Wi-Fi from Florence to Boston?

    Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company has the most timely service from Florence to Boston?

    According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Florence to Boston?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/26
$240
11/27
$190
Today
$166
11/29
$248
11/30
$344
12/01
$187
12/02
$121
12/03
No data
busbud logoThe cheapest trip from Florence, SC, US to Boston, MA, US was searched and found on Dec 2, 2025 with a price of $121

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Boston, MA, US, as early as possible.

You can expect to pay from $121 to $344 for a bus ticket from Florence, SC, US to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $121 which is on 2025-12-02.

What's the cheapest way to go from Florence, SC, US to Boston, MA, US?

busbud logoThe bus is the cheapest travel choice for this destination

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