What is the distance between Florence and Boston?

It's about 1176 km (729 miles) from Florence to Boston.

What are the departure and arrival locations for buses traveling from Florence to Boston?

Buses departing from Florence Bus Station in Florence will take you to Back Bay Station in Boston.

Bus Florence to Boston from $152 | Refundable Tickets

Previously seen trips

Next departures for Florence to Boston on November 24
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	4:15pm	Bus station	22h 10m	2:25pm	Boston (South Station)	No tags
FlixBus + Greyhound	Bus	4:15pm	Bus station	1d 3h	7:20pm	151 Steel Pl, Cambridge	No tags
Greyhound + FlixBus	Bus	4:15pm	Bus station	1d 3h	7:20pm	151 Steel Pl, Cambridge	No tags
	Bus	4:15pm	Bus station	22h 10m	2:25pm	Boston (South Station)	No tags
	Bus	4:15pm	Bus station	22h 10m	2:25pm	Boston (South Station)	No tags

Compare 2 ways to go from Florence to Boston

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Boston. The journey takes about 19 hours 32 minutes, and with fares starting at just $206, it presents an excellent value for a comfortable ride.

5train per day

19h 32mAverage Duration

1180 kmDistance

107kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$145 - $788	Average Duration1d 2h	CO₂ emissions 30kg CO₂e
Train	Average Price$206 - $959	Average Duration19h 32m	CO₂ emissions 107kg CO₂e

Where are the popular stops in Florence and Boston?

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Stops in Boston

A
Back Bay Station
145 Dartmouth St, Boston, MA 02116, USA
Visit page
B
North Station
100 Legends Way, Boston, MA 02114, USA
Visit page
C
South Station
700 Atlantic Ave, Boston, MA 02205, USA
Visit page
D
Copley Square
115-127 St James Ave, Boston, MA 02116, USA
E
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA
F
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA

Compare bus companies

FlixBus

3.5/511,432 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Greyhound

3.5/587,393 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about travelling from Florence, SC, US to Boston, MA, US by bus

What is the distance between Florence and Boston?
It's about 1176 km (729 miles) from Florence to Boston.
What are the departure and arrival locations for buses traveling from Florence to Boston?
Buses departing from Florence Bus Station in Florence will take you to Back Bay Station in Boston.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-22

$229

11-23

$267

Today

$213

11-25

$188

11-26

$347

11-27

$275

11-28

$241

11-29

$358

The cheapest trip from Florence, SC, US to Boston, MA, US was searched and found on Nov 25, 2025 with a price of $188

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Boston, MA, US, as early as possible.

You can expect to pay from $188 to $358 for a bus ticket from Florence, SC, US to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $188 which is on 2025-11-25.