Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Florence, SC | Baltimore Downtown Bus Station | Cheapest | ||||
 | Bus | 2301 W Lucas St. | O'Donnell St. & Travel Plaza, Infront of TA Gas station | Fastest | ||||
| Bus | 2301 W Lucas St. | O'Donnell St. & Travel Plaza, Infront of TA Gas station | No tags | ||||
 | Bus | Bus station | Baltimore Downtown Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Bus station | Baltimore Bus Stop | No tags |
Last refresh of the prices: Today at 6:15 AM EST.
Compare 2 ways to go from Florence to Baltimore
Among the sustainable travel choices, the bus stands out as the good way to reach Baltimore. The journey takes about 10 hours 15 minutes and with fares starting at just $64, it presents an excellent value for a comfortable ride.
Where are the popular stops in Florence and Baltimore?
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Stops in Baltimore
- A
Baltimore Downtown Bus Station
2110 Haines St, Baltimore, MD 21230, United States - B7 St Paul St, Baltimore, MD 21201, USA
- D1578 Maryland Ave, Baltimore, MD 21201, USA
Compare bus companies
Frequently asked questions about traveling from Florence, SC, US to Baltimore by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Florence to Baltimore?
The cheapest bus tickets from Florence to Baltimore start from $64. The average price for this route is around $110. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to Baltimore?
The average bus trip duration from Florence to Baltimore is 10h 15m, covering a distance of 392 miles (632 km). The quickest bus can get you there in 8h 45m and is operated by Wanda Coach.
Which bus companies service the Florence to Baltimore route?
Several major bus companies operate on this route with 5 buses available per day, including services from Wanda Coach, Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Florence to Baltimore?
The earliest bus departs from Florence to Baltimore at 12:05am. And the latest bus departs at 9:00pm.
What are the CO₂ emissions for the bus trip from Florence to Baltimore?
A bus trip from Florence to Baltimore generates an estimated 16 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Florence to Baltimore?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from Florence to Baltimore?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Florence to Baltimore?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Florence to Baltimore?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Baltimore was searched and found on Dec 2, 2025 with a price of $81To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Baltimore, as early as possible.
You can expect to pay from $81 to $209 for a bus ticket from Florence, SC, US to Baltimore based on the last 2 days. You can expect to find the cheapest price for the trip at $81 which is on 2025-12-02.
What's the cheapest way to go from Florence, SC, US to Baltimore?
The bus is the cheapest travel choice for this destination
