Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | 2301 W Lucas St. | O'Donnell St. & Travel Plaza, Infront of TA Gas station | CheapestFastest | ||||
| Bus | 2301 W Lucas St. | O'Donnell St. & Travel Plaza, Infront of TA Gas station | No tags | ||||
 | Bus | Bus station | Baltimore Downtown Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Bus station | Baltimore Bus Stop | No tags |
Last refresh of the prices: Yesterday at 13:58 EST.
Compare 2 ways to travel from Florence to Baltimore
Among the sustainable travel choices, the bus stands out as a good way to reach Baltimore. The journey takes about 10 hours 15 minutes and with fares starting at just £50, it presents an excellent value for a comfortable ride.
Where are the popular stops in Florence and Baltimore?
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Stops in Baltimore
- A
Baltimore Downtown Bus Station
2110 Haines St, Baltimore, MD 21230, United States - B7 St Paul St, Baltimore, MD 21201, USA
- D1578 Maryland Ave, Baltimore, MD 21201, USA
Compare bus companies
Frequently asked questions about travelling by bus from Florence, SC, US to Baltimore
How far is Baltimore from Florence by coach?
The distance between Florence and Baltimore by coach is approximately 389 miles (627 km).
Is there a way to reach Baltimore from Florence without flying?
You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You also have the option of utilising carpooling services.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Baltimore was searched and found on 26 Nov 2025 with a price of £65To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Baltimore as early as possible.
You can expect to pay from £65 to £188 for a bus ticket from Florence, SC, US to Baltimore based on the last 2 days. You can expect to find the cheapest price for the trip at £65, which is on 2025-11-26.
What's the cheapest way to go from Florence, SC, US to Baltimore?
The bus is the cheapest travel choice for this destination
