Find coaches from Tupelo to Chicago

Next departures

Next departures from Tupelo to Chicago on 4 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
    		Tupelo (Brothers Quick Stop)
    		Chicago 95Th & Dan RyanCheapest
    Greyhound Lines, Inc. + FlixBus
      		Tupelo (Brothers Quick Stop)
      		Chicago 95Th & Dan RyanFastest
      Greyhound Lines, Inc. + FlixBus
        		Tupelo (Brothers Quick Stop)
        		Downtown Greyhound StationNo tags
        Greyhound Lines, Inc.
          		Tupelo (Brothers Quick Stop)
          		Downtown Greyhound StationNo tags
          Greyhound Lines, Inc. + FlixBus
            		Tupelo (Brothers Quick Stop)
            		Downtown Greyhound StationNo tags

            Last refresh of the prices: Yesterday at 9:49 PM CST.

            Accepted payments

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            Get from Tupelo to Chicago

            This route is served by bus only

            The journey takes about 23 hours 5 minutes, and with fares starting at just R 1 361, it presents an excellent value for a comfortable ride.

            10bus per day
            23h 5mAverage duration
            838 kmDistance
            21kgCO₂ emissions

            Bus Tupelo to Chicago: Trip Overview

            Average ticket priceR 2 594
            Average bus trip duration23h 5m
            Number of daily buses10
            Earliest bus departure05:35
            Distance838 km
            Latest bus departure23:15

            Tupelo to Chicago Bus

            With Busbud, comparing and booking tickets for a bus from Tupelo to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

            We make sure you can find a bus service from Tupelo to Chicago from the most reliable bus companies operating this trip.

            Discover how much the bus trip from Tupelo to Chicago will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

            Frequently asked questions on the trip Tupelo - Chicago

            1. How much does a bus ticket from Tupelo to Chicago cost?

              The bus ticket price from Tupelo to Chicago starts at R 1 361. The best way to find cheap bus tickets from Tupelo to Chicago is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

            2. How long is the bus ride from Tupelo to Chicago?

              The average travel time between Tupelo and Chicago is around 23h 5m, although the fastest bus will take about 16h 15m. This is the time it takes to travel the 853 km that separates the two cities.

            3. How many daily bus connections are there between Tupelo and Chicago?

              The number of buses from Tupelo to Chicago can differ depending on the day of the week. On average, there are 10 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Tupelo to Chicago by comparing and selecting the bus that fits your travel style and budget on Busbud.

            4. Which bus companies travel from Tupelo to Chicago?

              When taking the bus from Tupelo to Chicago, you can travel comfortably and safely with Greyhound.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            01/11
            No data
            02/11
            No data
            Today
            R 2 493
            04/11
            R 2 431
            05/11
            No data
            06/11
            No data
            07/11
            No data
            08/11
            No data
            busbud logoThe cheapest trip from Tupelo to Chicago was searched and found on 04 Nov 2025 with a price of R 2 431

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to Chicago as early as possible.

            You can expect to pay from R 2 431 to R 4 339 for a bus ticket from Tupelo to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 431, which is on 2025-11-04.

            About Bus Travel

            Bus Travel Tips

            Meet and talk to locals at the bus stations while travelling from Tupelo to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

            Start sightseeing the minute your bus leaves the station. If you're on the night bus from Tupelo to Chicago, get comfy and count the stars.

            Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Tupelo to Chicago will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

            Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Tupelo to Chicago.

            Did you know?

            The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

            Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

            It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

            Will you be returning to Tupelo by bus?

            Bus from Chicago to Tupelo

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