Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Tupelo (Brothers Quick Stop) | Chicago 95Th & Dan Ryan | No tags | ||||
| Bus | Tupelo (Brothers Quick Stop) | 537-517 W. Jackson Blvd | No tags | ||||
| Bus | Tupelo (Brothers Quick Stop) | Downtown Greyhound Station | No tags | ||||
Greyhound + FlixBus | Bus | Tupelo (Brothers Quick Stop) | Chicago 95Th & Dan Ryan | No tags | ||||
FlixBus + Greyhound | Bus | Tupelo (Brothers Quick Stop) | Downtown Greyhound Station | No tags |
Get from Tupelo to Chicago
This route is served by bus only
The journey takes about 1 day, 35 minutes, and with fares starting at just £79, it presents an excellent value for a comfortable ride.
11bus per day
1d Average duration
520 milesDistance
21kgCO₂ emissions
Frequently asked questions about travelling by bus from Tupelo to Chicago
What's the distance between Tupelo and Chicago by coach?
The distance between Tupelo and Chicago by coach is approximately 529 miles (853 km).
How can I travel from Tupelo to Chicago avoiding air travel?
You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
24/11
£174
25/11
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Today
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27/11
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28/11
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29/11
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30/11
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01/12
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The cheapest trip from Tupelo to Chicago was searched and found on 24 Nov 2025 with a price of £174To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to Chicago as early as possible.
