Bus from Antofagasta to Santiago, CL: Tickets & Timetables

Next bus departures

Next departures from Antofagasta to Santiago on 2 January
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AndimarBus
    Terminal de Buses Cardenal Carlos Oviedo Cavada)
    Terminal San BorjaCheapest
    Cikbus ElitéBus
    Terminal Antofagasta
    Terminal de Buses San Borja - San Francisco de BorjaFastest
    Cikbus ElitéBus
    Terminal Antofagasta
    Terminal de Buses San Borja - San Francisco de BorjaNo tags
    Pluss ChileBus
    Terminal Antofagasta
    San BorjaNo tags
    AndimarBus
      Terminal de Buses Cardenal Carlos Oviedo Cavada)
      Terminal San BorjaNo tags

      Last refresh of the prices: Today at 12:43 AM -03.

      Get from Antofagasta to Santiago

      This route is served by bus only

      The journey takes about 18 hours 30 minutes, and with fares starting at just R 463, it presents an excellent value for a comfortable ride.

      46bus per day
      18h 30mAverage duration
      1095 kmDistance
      27kgCO₂ emissions

      Frequently asked questions about travelling from Antofagasta to Santiago, CL by bus

      Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

      1. How much is the bus ticket from Antofagasta to Santiago?

        The cheapest bus tickets from Antofagasta to Santiago start at R 463. The average price for this route is around R 920. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

      2. How long is the bus journey from Antofagasta to Santiago?

        The average bus journey time from Antofagasta to Santiago is 18h 30m, covering a distance of 1095 km. The fastest bus gets you there in 17h and is operated by Cikbus Elité.

      3. Which bus companies service the Antofagasta to Santiago route?

        Several major bus companies operate on this route with 46 buses available per day, including services from Pluss Chile, Pullman San Andres, Cikbus Elité, Buses Andimar.

      4. What is the earliest and latest departure time for the bus from Antofagasta to Santiago?

        The earliest bus departs from Antofagasta to Santiago at 00:05. And the latest bus departs at 23:55.

      5. What are the CO₂ emissions for the bus trip from Antofagasta to Santiago?

        A bus trip from Antofagasta to Santiago produces an estimated 27 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

      6. What is the best bus company from Antofagasta to Santiago?

        According to Busbud customers, the highest-rated bus company on this route is Buses Andimar, with an average rating of 4.1 out of 5 stars based on 56 reviews.

      7. Which bus company has the best Wi-Fi from Antofagasta to Santiago?

        Based on reviews on Busbud, the bus company Pluss Chile has the best Wi-Fi rating with a score of 1.3.

      8. Which bus company offers the most punctual service from Antofagasta to Santiago?

        According to Busbud traveller reviews, the most punctual bus company on this route is Buses Andimar, with a punctuality rating of 4.3 out of 5 stars.

      9. Which bus company has the cleanest buses from Antofagasta to Santiago?

        According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Pluss Chile, with a cleanliness rating of 4.5 out of 5 stars.

      Find cheapest prices for buses

      Price is for a one-way ticket for one passenger and based on past searches.

      Best price found
      02/01
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      06/01
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      Today
      R 524
      busbud logoThe cheapest trip from Antofagasta to Santiago, CL was searched and found on 01 Jan 2026 with a price of R 524

      To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Antofagasta to Santiago, CL as early as possible.

      You can expect to pay from R 524 to R 1 394 for a bus ticket from Antofagasta to Santiago, CL based on the last 0 days. You can expect to find the cheapest price for the trip at R 574, which is on 2026-01-02.

      Usually Pluss Chile will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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