Bus from Antofagasta to Santiago, CL: Tickets & Timetables

Next bus departures

Next departures from Antofagasta to Santiago on 29 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Cikbus ElitéBus
Terminal Antofagasta
Terminal de Buses San Borja - San Francisco de BorjaCheapest
Cikbus ElitéBus
Terminal Antofagasta
Terminal de Buses San Borja - San Francisco de BorjaFastest
Cikbus ElitéBus
Terminal Antofagasta
Terminal de Buses San Borja - San Francisco de BorjaNo tags
Pluss ChileBus
Terminal Antofagasta
San BorjaNo tags
Pullman San AndrésBus
Terminal Carlos Oviedo Cavada
San BorjaNo tags

Last refresh of the prices: Today at 02:01 -03.

Get from Antofagasta to Santiago

This route is served by bus only

The journey takes about 18 hours 20 minutes, and with fares starting at just £21, it presents an excellent value for a comfortable ride.

49bus per day
18h 20mAverage duration
679 milesDistance
27kgCO₂ emissions

Frequently asked questions about travelling by bus from Antofagasta to Santiago, CL

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

  1. How much is the bus ticket from Antofagasta to Santiago?

    The cheapest coach tickets from Antofagasta to Santiago start from £21. The average price for this route is around £37. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus journey from Antofagasta to Santiago?

    The average bus journey time from Antofagasta to Santiago is 18h 20m, covering a distance of 679 miles. The fastest bus can take you there in 17h and is operated by Pullman San Andres.

  3. Which bus companies service the Antofagasta to Santiago route?

    Several major bus companies operate on this route with 49 buses available per day, including services from Pluss Chile, Pullman San Andres, Cikbus Elité, Buses Andimar, Clikbus.

  4. What is the earliest and latest departure time for the bus from Antofagasta to Santiago?

    The earliest bus departs from Antofagasta to Santiago at 00:05. And the latest bus departs at 23:55.

  5. What are the CO₂ emissions for the bus trip from Antofagasta to Santiago?

    A bus journey from Antofagasta to Santiago produces an estimated 27 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

  6. Which is the best bus company from Antofagasta to Santiago?

    According to Busbud customers, the highest-rated bus company on this route is Clikbus, with an average rating of 4.3 out of 5 stars based on 3 reviews.

  7. Which company has the best Wi-Fi from Antofagasta to Santiago?

    Based on Busbud reviews, the bus company Pluss Chile has the best Wi-Fi rating with a score of 1.6.

  8. Which bus company offers the most punctual service from Antofagasta to Santiago?

    According to Busbud traveller reviews, the most punctual bus company on this route is Clikbus, with a punctuality rating of 5.0 out of 5 stars.

  9. Which bus company has the cleanest buses from Antofagasta to Santiago?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Pluss Chile, with a cleanliness rating of 4.6 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
26/11
£28
27/11
£26
Today
£25
29/11
£25
30/11
£25
01/12
£20
02/12
£20
03/12
£20
busbud logoThe cheapest trip from Antofagasta to Santiago, CL was searched and found on 1 Dec 2025 with a price of £20

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Antofagasta to Santiago, CL as early as possible.

You can expect to pay from £20 to £51 for a bus ticket from Antofagasta to Santiago, CL based on the last 2 days. You can expect to find the cheapest price for the trip at £20, which is on 2025-12-01.

Usually Pluss Chile will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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