Find coaches from Prague to Brussels

Next bus departures

Next departures from Prague to Brussels on 20 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixbusBus
Prague (Main Railway Station)
Brussels North Train StationCheapest
FlixbusBus
Prague (Na Knížecí)
Brussels North Train StationFastest
BlaBlaCar BusBus
    		Florenc
    		Brussels-South (Gare du Midi)No tags
    FlixbusBus
    		Prague (Central Bus Station Florenc)
    		Brussels AirportNo tags
    FlixbusBus
    		Prague (Central Bus Station Florenc)
    		Brussels AirportNo tags

    Last refresh of the prices: Last Sunday at 09:11 CET.

    Compare 2 ways to travel from Prague to Brussels

    We recommend taking the bus

    Among the sustainable travel choices, the bus stands out as a good way to reach Brussels. The journey takes about 18 hours 40 minutes and with fares starting at just £35, it presents an excellent value for a comfortable ride.

    14bus per day
    18h 40mAverage duration
    440 milesDistance
    18kgCO₂ emissions
    Bus
    		Average price£35 - £194Average duration18h 40m
    18kg CO₂e
    Train
    		Average price£48 - £225Average duration15h 21m
    17kg CO₂e

    Frequently asked questions about travelling by bus from Prague to Brussels

    1. How far is Brussels from Prague by coach?

      The journey from Prague to Brussels by coach covers an approximate distance of 446 miles (719 km).

    2. What is the best way to go from Prague to Brussels without flying?

      To travel from Prague to Brussels without flying, you can take the coaches. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

    Find cheapest prices for buses

    Price is for a one-way ticket for one passenger and based on past searches.

    Best price found
    16/11
    £54
    17/11
    £49
    Today
    £47
    19/11
    No data
    20/11
    £40
    21/11
    £38
    22/11
    No data
    23/11
    £56
    busbud logoThe cheapest trip from Prague to Brussels was searched and found on 21 Nov 2025 with a price of £38

    To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Brussels as early as possible.

    You can expect to pay from £38 to £87 for a bus ticket from Prague to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at £38, which is on 2025-11-21.

    What's the cheapest way to go from Prague to Brussels?

    busbud logoThe bus is the cheapest travel choice for this destination

    People from around the world trust Busbud

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