How much is the bus ticket from Prague to Brussels?

The cheapest bus tickets from Prague to Brussels start at R 749. The average price for this route is around R 1 367. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

How long is the bus journey from Prague to Brussels?

The average bus journey time from Prague to Brussels is 18h 40m, covering a distance of 710 km. The fastest bus gets you there in 12h and is operated by RegioJet .

Which bus companies service the Prague to Brussels route?

Several major bus companies operate on this route with 17 buses available per day, including services from FlixBus , BlaBlaCar Bus , RegioJet .

What is the earliest and latest departure time for the bus from Prague to Brussels?

The earliest bus departs from Prague to Brussels at 00:10. And the latest bus departs at 23:05.

What are the CO₂ emissions for the bus trip from Prague to Brussels?

A bus trip from Prague to Brussels produces an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

What is the best bus company from Prague to Brussels?

According to Busbud customers, the highest-rated bus company on this route is RegioJet , with an average rating of 4.1 out of 5 stars based on 1062 reviews.

Which bus company has the best Wi-Fi from Prague to Brussels?

Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.

Which bus company offers the most punctual service from Prague to Brussels?

According to Busbud traveller reviews, the most punctual bus company on this route is RegioJet , with a punctuality rating of 4.0 out of 5 stars.

Which bus company has the cleanest buses from Prague to Brussels?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet , with a cleanliness rating of 4.4 out of 5 stars.

Bus Prague to Brussels from R 714 | Refundable Tickets

Next bus departures

Next departures from Prague to Brussels on 25 December
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	18:00	Florenc	12h	06:00	Brussels South (Gare du Midi)	CheapestFastest
Bus	19:00	Florenc	18h 30m	13:30	Brussels-South (Gare du Midi)	No tags
Bus	13:35	Florenc	1d 6h	19:55	Brussels North Train Station	No tags

Next departures from Prague to Brussels on 26 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	19:00	Florenc	18h 30m	13:30	Brussels-South (Gare du Midi)	CheapestFastest
	Bus	13:35	Florenc	1d 6h	19:55	Brussels North Train Station	No tags

Next departures from Prague to Brussels on 27 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	19:00	Florenc	18h 30m	13:30	Brussels-South (Gare du Midi)	CheapestFastest

Next departures from Prague to Brussels on 28 December
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	16:15	Prague (Central Bus Station Florenc)	15h 5m	07:20	Brussels South (Gare du Midi)	Cheapest
Bus	04:10	Prague (Na Knížecí)	13h 55m	18:05	Brussels North Train Station	Fastest
Bus	19:00	Florenc	18h 30m	13:30	Brussels-South (Gare du Midi)	No tags
Bus	07:15	Prague (Central Bus Station Florenc)	22h 10m	05:25	Brussels Airport	No tags
Bus	13:35	Florenc	1d 6h	19:55	Brussels North Train Station	No tags

Last refresh of the prices: Today at 8:16 AM CET.

Compare 2 ways to travel from Prague to Brussels

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Brussels. The journey takes about 18 hours 40 minutes and with fares starting at just R 749, it presents an excellent value for a comfortable ride.

17bus per day

18h 40mAverage duration

710 kmDistance

18kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average priceR 749 - R 4 222	Average duration18h 40m	CO₂ emissions 18kg CO₂e
Train	Average priceR 1 047 - R 5 168	Average duration15h 18m	CO₂ emissions 17kg CO₂e

Where are the popular stops in Prague and Brussels?

Stops in Prague

A
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
Visit page
B
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic
Visit page
C
Tomíčkova
Tomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
Visit page
D
PRG Airport
Aviatická, 161 08, Praha 6, Czechia
Visit page
E
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic
F
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia
Visit page

Stops in Brussels

A
Brussels South (Gare du Midi)
Rue de France 85, 1060 Saint-Gilles, Belgium
Visit page
B
Brux-Nord
Boulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
Visit page
C
Congrès
Pachecolaan 5, 1000 Brussel, Belgium
Visit page
D
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium

Compare bus companies

FlixBus

3.5/511 693 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

WiFi2.7

BlaBlaCar Bus

3.5/511 269 reviews

Staff4.4

Timeliness3.7

Cleanliness4.3

WiFi2.6

RegioJet

4/51 062 reviews

Staff4.5

Timeliness4

Cleanliness4.4

WiFi3.8

BE Bus Companies: FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from Prague to Brussels by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

How much is the bus ticket from Prague to Brussels?
The cheapest bus tickets from Prague to Brussels start at R 749. The average price for this route is around R 1 367. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Prague to Brussels?
The average bus journey time from Prague to Brussels is 18h 40m, covering a distance of 710 km. The fastest bus gets you there in 12h and is operated by RegioJet.
Which bus companies service the Prague to Brussels route?
Several major bus companies operate on this route with 17 buses available per day, including services from FlixBus, BlaBlaCar Bus, RegioJet.
What is the earliest and latest departure time for the bus from Prague to Brussels?
The earliest bus departs from Prague to Brussels at 00:10. And the latest bus departs at 23:05.
What are the CO₂ emissions for the bus trip from Prague to Brussels?
A bus trip from Prague to Brussels produces an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Prague to Brussels?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1062 reviews.
Which bus company has the best Wi-Fi from Prague to Brussels?
Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.
Which bus company offers the most punctual service from Prague to Brussels?
According to Busbud traveller reviews, the most punctual bus company on this route is RegioJet, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Prague to Brussels?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

20/12

R 2 264

21/12

R 1 936

Today

R 1 938

23/12

No data

24/12

R 2 231

25/12

R 1 026

26/12

R 2 675

27/12

R 2 363

The cheapest trip from Prague to Brussels was searched and found on 25 Dec 2025 with a price of R 1 026

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Brussels as early as possible.

You can expect to pay from R 1 026 to R 2 878 for a bus ticket from Prague to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 026, which is on 2025-12-25.

Usually BlaBlaCar Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.