Find coaches from Prague to Brussels

Next departures

Next departures from Prague to Brussels on 2 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
BlaBlaCar Bus
    		Florenc
    		Brussels-South (Gare du Midi)CheapestFastest
    BlaBlaCar Bus
      		Florenc
      		Brussels North Train StationNo tags

      Last refresh of the prices: Yesterday at 10:41 AM CET.

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      Compare 2 ways to travel from Prague to Brussels

      We recommend taking the bus

      Among the sustainable travel choices, the bus stands out as a good way to reach Brussels. The journey takes about 18 hours 30 minutes and with fares starting at just US$44, it presents an excellent value for a comfortable ride.

      17bus per day
      18h 30mAverage duration
      708 kmDistance
      18kgCO₂ emissions
      Bus
      		Average priceUS$44 - US$243Average duration18h 30m
      18kg CO₂e
      Train
      		Average priceUS$62 - US$262Average duration15h 10m
      17kg CO₂e

      Bus Prague to Brussels: Trip Overview

      Average ticket priceUS$75
      Average bus trip duration18h 30m
      Number of daily buses17
      Earliest bus departure00:10
      Distance708 km
      Latest bus departure23:05

      Prague to Brussels Bus

      With Busbud, comparing and booking tickets for a bus from Prague to Brussels is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

      We make sure you can find a bus service from Prague to Brussels from the most reliable bus companies operating this trip.

      Whether it is cheap bus tickets or more luxurious buses going to Brussels from Prague, we help you find what you're looking for based on how much of a budget you have.

      Frequently asked questions on the trip Prague - Brussels

      1. How much does a bus ticket from Prague to Brussels cost?

        The bus ticket price from Prague to Brussels starts at US$44. The best way to find cheap bus tickets from Prague to Brussels is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

      2. How long is the bus ride from Prague to Brussels?

        The average travel time between Prague and Brussels is around 18h 30m, although the fastest bus will take about 12h. This is the time it takes to travel the 719 km that separates the two cities.

      3. How many daily bus connections are there between Prague and Brussels?

        The number of buses from Prague to Brussels can differ depending on the day of the week. On average, there are 17 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Prague to Brussels by comparing and selecting the bus that fits your travel style and budget on Busbud.

      4. Which bus companies travel from Prague to Brussels?

        When taking the bus from Prague to Brussels, you can travel comfortably and safely with FlixBus, BlaBlaCar Bus, RegioJet.

      5. What are the departure and arrival stations when taking the bus from Prague to Brussels?

        Buses travelling between Prague and Brussels leave from PRG Airport or Florenc and arrive at Brussels South (Gare du Midi), Brux-Nord, Congrès.

      Find cheapest prices for buses

      Price is for a one-way ticket for one passenger and based on past searches.

      Best price found
      30/10
      US$80
      31/10
      US$72
      Today
      US$137
      02/11
      US$118
      03/11
      No data
      04/11
      US$60
      05/11
      No data
      06/11
      US$91
      busbud logoThe cheapest trip from Prague to Brussels was searched and found on 04 Nov 2025 with a price of US$60

      To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Brussels as early as possible.

      You can expect to pay from US$60 to US$167 for a bus ticket from Prague to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at US$60, which is on 2025-11-04.

      About Bus Travel

      Bus Travel Tips

      Meet and talk to locals at the bus stations while travelling from Prague to Brussels.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

      Start sightseeing the minute your bus leaves the station. If you're on the night bus from Prague to Brussels, get comfy and count the stars.

      Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Prague to Brussels.

      Make a music playlist for your bus ride from Prague to Brussels, and enjoy the scenery to tunes from your own personal soundtrack.

      Did you know?

      One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

      It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

      The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

      What's the cheapest way to go from Prague to Brussels?

      busbud logoThe bus is the cheapest travel choice for this destination

      Will you be returning to Prague by bus?

      Bus from Brussels to Prague

      You can also go to Brussels by train

      Train from Prague to Brussels

      Why choose Busbud?

      The Best Way To Book Bus and Train Tickets

      Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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