How much is the bus ticket from Prague to Brussels?

The cheapest bus tickets from Prague to Brussels start from $62. The average price for this route is around $115. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Prague to Brussels?

The average bus travel time from Prague to Brussels is 18h 40m, covering a distance of 698 km. The quickest bus can get you there in 12h and is operated by RegioJet .

Which bus companies service the Prague to Brussels route?

Several major bus companies operate on this route with 17 buses available per day, including services from FlixBus , BlaBlaCar Bus , RegioJet .

What are the earliest and latest departure times for the bus from Prague to Brussels?

The earliest bus departs from Prague to Brussels at 12:10am. And the latest bus departs at 11:05pm.

What are the CO₂ emissions for the bus trip from Prague to Brussels?

A bus trip from Prague to Brussels generates an estimated 17 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

What is the best bus company from Prague to Brussels?

According to Busbud customers, the highest-rated bus company on this route is RegioJet , with an average rating of 4.1 out of 5 stars based on 1062 reviews.

Which bus company has the best Wi-Fi from Prague to Brussels?

Based on Busbud reviews, the bus company RegioJet has the highest Wi-Fi rating with a score of 3.8.

Which bus company has the best on-time performance from Prague to Brussels?

According to Busbud traveller reviews, the most punctual bus company on this route is RegioJet , with a punctuality rating of 4.0 out of 5 stars.

Which bus company has the cleanest buses from Prague to Brussels?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet , with a cleanliness rating of 4.4 out of 5 stars.

Bus Prague to Brussels from $59 | Refundable Tickets

Next bus departures

Next departures for Prague to Brussels on December 25
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	6:00pm	Florenc	12h	6:00am	Brussels South (Gare du Midi)	CheapestFastest
Bus	7:00pm	Florenc	18h 30m	1:30pm	Brussels-South (Gare du Midi)	No tags
Bus	1:35pm	Florenc	1d 6h	7:55pm	Brussels North Train Station	No tags

Next departures for Prague to Brussels on December 26
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	7:00pm	Florenc	18h 30m	1:30pm	Brussels-South (Gare du Midi)	CheapestFastest
	Bus	1:35pm	Florenc	1d 6h	7:55pm	Brussels North Train Station	No tags

Next departures for Prague to Brussels on December 27
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	7:00pm	Florenc	18h 30m	1:30pm	Brussels-South (Gare du Midi)	CheapestFastest

Next departures for Prague to Brussels on December 28
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	4:15pm	Prague (Central Bus Station Florenc)	15h 5m	7:20am	Brussels South (Gare du Midi)	Cheapest
Bus	4:10am	Prague (Na Knížecí)	13h 55m	6:05pm	Brussels North Train Station	Fastest
Bus	7:00pm	Florenc	18h 30m	1:30pm	Brussels-South (Gare du Midi)	No tags
Bus	7:15am	Prague (Central Bus Station Florenc)	22h 10m	5:25am	Brussels Airport	No tags
Bus	1:35pm	Florenc	1d 6h	7:55pm	Brussels North Train Station	No tags

Next departures for Prague to Brussels on December 29
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	4:15pm	Prague (Central Bus Station Florenc)	15h 5m	7:20am	Brussels South (Gare du Midi)	Cheapest
Bus	4:10am	Prague (Na Knížecí)	13h 55m	6:05pm	Brussels North Train Station	Fastest
Bus	7:15am	Prague (Central Bus Station Florenc)	22h 10m	5:25am	Brussels Airport	No tags
Bus	6:00pm	Prague (Central Bus Station Florenc)	17h 15m	11:15am	Brussels Airport	No tags
Bus	11:00pm	Prague (Central Bus Station Florenc)	19h 35m	6:35pm	Brussels Airport	No tags

Next departures for Prague to Brussels on December 30
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	4:15pm	Prague (Central Bus Station Florenc)	15h 5m	7:20am	Brussels South (Gare du Midi)	Cheapest
Bus	4:10am	Prague (Na Knížecí)	13h 55m	6:05pm	Brussels North Train Station	Fastest
Bus	7:15am	Prague (Central Bus Station Florenc)	22h 10m	5:25am	Brussels Airport	No tags
Bus	6:00pm	Prague (Central Bus Station Florenc)	17h 15m	11:15am	Brussels Airport	No tags
Bus	11:00pm	Prague (Central Bus Station Florenc)	19h 35m	6:35pm	Brussels Airport	No tags

Last refresh of the prices: Today at 12:28 AM CET.

Compare 2 ways to go from Prague to Brussels

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Brussels. The journey takes about 15 hours 18 minutes, and with fares starting at just $87, it presents an excellent value for a comfortable ride.

2train per day

15h 18mAverage Duration

718 kmDistance

17kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$62 - $296	Average Duration18h 40m	CO₂ emissions 17kg CO₂e
Train	Average Price$87 - $424	Average Duration15h 18m	CO₂ emissions 17kg CO₂e

Where are the popular stops in Prague and Brussels?

Stops in Prague

A
PRG Airport
Aviatická, 161 08, Praha 6, Czechia
Visit page
B
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic
C
Tomíčkova
Tomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
Visit page
D
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
Visit page
E
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic
Visit page
F
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia
Visit page

Stops in Brussels

A
Brussels South (Gare du Midi)
Rue de France 85, 1060 Saint-Gilles, Belgium
Visit page
B
Brux-Nord
Boulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
Visit page
C
Congrès
Pachecolaan 5, 1000 Brussel, Belgium
Visit page
D
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium

Compare bus companies

FlixBus

3.5/511,730 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

BlaBlaCar Bus

3.5/511,286 reviews

Staff4.4

Timeliness3.7

Cleanliness4.3

Wifi2.6

RegioJet

4/51,062 reviews

Staff4.5

Timeliness4

Cleanliness4.4

Wifi3.8

BE Bus Companies: FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from Prague to Brussels by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Prague to Brussels?
The cheapest bus tickets from Prague to Brussels start from $62. The average price for this route is around $115. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Prague to Brussels?
The average bus travel time from Prague to Brussels is 18h 40m, covering a distance of 698 km. The quickest bus can get you there in 12h and is operated by RegioJet.
Which bus companies service the Prague to Brussels route?
Several major bus companies operate on this route with 17 buses available per day, including services from FlixBus, BlaBlaCar Bus, RegioJet.
What are the earliest and latest departure times for the bus from Prague to Brussels?
The earliest bus departs from Prague to Brussels at 12:10am. And the latest bus departs at 11:05pm.
What are the CO₂ emissions for the bus trip from Prague to Brussels?
A bus trip from Prague to Brussels generates an estimated 17 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Prague to Brussels?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1062 reviews.
Which bus company has the best Wi-Fi from Prague to Brussels?
Based on Busbud reviews, the bus company RegioJet has the highest Wi-Fi rating with a score of 3.8.
Which bus company has the best on-time performance from Prague to Brussels?
According to Busbud traveller reviews, the most punctual bus company on this route is RegioJet, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Prague to Brussels?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12-23

No data

12-24

$131

Today

$85

12-26

$220

12-27

$203

12-28

$122

12-29

$126

12-30

$117

The cheapest trip from Prague to Brussels was searched and found on Dec 25, 2025 with a price of $85

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Brussels, as early as possible.

You can expect to pay from $85 to $390 for a bus ticket from Prague to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at $117 which is on 2025-12-30.

Usually BlaBlaCar Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.