Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Bus station | Chicago 95Th & Dan Ryan | No tags | ||||
| Bus | Bus station | Downtown Greyhound Station | No tags | ||||
| Bus | Bus station | 537-517 W. Jackson Blvd | No tags | ||||
Greyhound + FlixBus | Bus | Florence, SC | 537-517 W. Jackson Blvd | No tags | ||||
FlixBus + Greyhound | Bus | Florence, SC | Chicago 95Th & Dan Ryan | No tags |
Compare 2 ways to travel from Florence to Chicago
Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 1 day, 3 hours 30 minutes and with fares starting at just £96, it presents an excellent value for a comfortable ride.
Where are the popular stops in Florence and Chicago?
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Frequently asked questions about travelling by bus from Florence, SC, US to Chicago
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Florence to Chicago?
The cheapest coach tickets from Florence to Chicago start from £96. The average price for this route is around £164. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Florence to Chicago?
The average bus journey time from Florence to Chicago is 1d 3h, covering a distance of 672 miles. The fastest bus can take you there in 23h 10m and is operated by Greyhound.
Which bus companies service the Florence to Chicago route?
What is the earliest and latest departure time for the bus from Florence to Chicago?
The earliest bus departs from Florence to Chicago at 00:05. And the latest bus departs at 16:30.
What are the CO₂ emissions for the bus trip from Florence to Chicago?
A bus journey from Florence to Chicago produces an estimated 27 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Florence to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which company has the best Wi-Fi from Florence to Chicago?
Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Florence to Chicago?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Florence to Chicago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Chicago was searched and found on 27 Nov 2025 with a price of £168To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Chicago as early as possible.
You can expect to pay from £168 to £449 for a bus ticket from Florence, SC, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at £264, which is on 2025-11-30.
What's the cheapest way to go from Florence, SC, US to Chicago?
The bus is the cheapest travel choice for this destination
