Train tickets from Florence, SC, US to Chicago

Previously seen journeys

Next departures from Florence to Chicago on 23 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Florence Station
Chicago (Union Station), ILNo tags
AmtrakTrain
Florence Station
Chicago (Union Station), ILNo tags
AmtrakTrain
Florence Station
Chicago (Union Station), ILNo tags
AmtrakTrain
Florence Station
Chicago (Union Station), ILNo tags
AmtrakTrain
Florence Station
Chicago (Union Station), ILNo tags

Compare 2 ways to travel from Florence to Chicago

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 1 day, 4 hours 55 minutes and with fares starting at just £97, it presents an excellent value for a comfortable ride.

8bus per day
1d 4hAverage duration
672 milesDistance
27kgCO₂ emissions
Average price£97 - £277Average duration1d 4h
27kg CO₂e
Average price£146 - £1,522Average duration1d 11h
100kg CO₂e

Frequently asked questions about travelling from Florence, SC, US to Chicago by train

  1. How much does a cheap train ticket from Florence to Chicago cost?

    The average train ticket price from Florence to Chicago is £300. The best way to find cheap train tickets from Florence to Chicago is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the train trip from Florence to Chicago?

    A train trip between Florence and Chicago is around 1d 11h, although the fastest train will take about 1d 10h. This is the time it takes to travel the 684 miles that separates the two cities.

  3. How many daily train are there between Florence and Chicago?

    The number of trains from Florence to Chicago can differ depending on the day of the week. On average, there are 2. Some trains are direct while others include transferring trains. Simplify your train trip from Florence to Chicago by comparing and selecting the train that fits your travel style and budget on Busbud.

  4. Which train companies travel from Florence to Chicago?

    When taking the train from Florence to Chicago, you can travel comfortably and safely with Amtrak.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
21/11
£387
22/11
No data
Today
No data
24/11
No data
25/11
£266
26/11
No data
27/11
No data
28/11
No data
busbud logoThe cheapest trip from Florence, SC, US to Chicago was searched and found on 25 Nov 2025 with a price of £266

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Florence, SC, US to Chicago as early as possible.

You can expect to pay from £266 to £1,592 for a train ticket from Florence, SC, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at £266, which is on 2025-11-25.

People from around the world trust Busbud