Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Florence Station | Chicago (Union Station), IL | CheapestFastest | ||||
| Train | Florence Station | Chicago (Union Station), IL | No tags | ||||
| Train | Florence Station | Chicago (Union Station), IL | No tags | ||||
| Train | Florence Station | Chicago (Union Station), IL | No tags |
Last refresh of the prices: Today at 9:43 AM EST.
Compare 2 ways to go from Florence to Chicago
Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 1 day, 4 hours 55 minutes, and with fares starting at just $178, it presents an excellent value for a comfortable ride.
Train companies
Based on 5597 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at $268
Frequently asked questions about travelling from Florence, SC, US to Chicago by train
How much does a cheap train ticket from Florence to Chicago cost?
The average train ticket price from Florence to Chicago is $552. The best way to find cheap train tickets from Florence to Chicago is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the trip from Florence to Chicago?
A train trip between Florence and Chicago is around 1d 11h, although the fastest train will take about 1d 10h. This is the time it takes to travel the 1102 km that separates the two cities.
How many daily trains are there between Florence and Chicago?
The number of trains from Florence to Chicago can differ depending on the day of the week. On average, there are 2. Some trains are direct while others include transferring trains. Simplify your train trip from Florence to Chicago by comparing and selecting the train that fits your travel style and budget on Busbud.
Which train companies travel from Florence to Chicago?
When taking the train from Florence to Chicago, you can travel comfortably and safely with Amtrak.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Chicago was searched and found on Nov 25, 2025 with a price of $490To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Florence, SC, US to Chicago, as early as possible.
You can expect to pay from $490 to $2,934 for a train ticket from Florence, SC, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $490 which is on 2025-11-25.
