Bus from Louisville to Chicago: Tickets & Schedules

Next bus departures

Next departures for Louisville to Chicago on December 2
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.Bus
Louisville, KY
Downtown Greyhound StationCheapest
FlixBusBus
Louisville, KY
Chicago 95Th & Dan RyanFastest
AmtrakBus
Louisville, KY
Chicago (Union Station), ILNo tags
Greyhound Lines, Inc.Bus
Louisville, KY
Downtown Greyhound StationNo tags
FlixBusBus
Louisville, KY
Downtown Greyhound StationNo tags

Last refresh of the prices: Today at 9:11 PM EST.

Get from Louisville to Chicago

This route is served by bus only

The journey takes about 7 hours 10 minutes, and with fares starting at just $58, it presents an excellent value for a comfortable ride.

18bus per day
7h 10mAverage Duration
434 kmDistance
11kgCO₂ emissions

Frequently asked questions about travelling from Louisville to Chicago by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Louisville to Chicago?

    The cheapest bus tickets from Louisville to Chicago start from $58. The average price for this route is around $78. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Louisville to Chicago?

    The average bus travel time from Louisville to Chicago is 7h 10m, covering a distance of 434 km. The quickest bus can get you there in 5h 20m and is operated by FlixBus.

  3. Which bus companies service the Louisville to Chicago route?

    Several major bus companies operate on this route with 18 buses available per day, including services from Greyhound, FlixBus, Amtrak.

  4. What are the earliest and latest departure times for the bus from Louisville to Chicago?

    The earliest bus departs from Louisville to Chicago at 1:50am. And the latest bus departs at 7:30pm.

  5. What are the CO₂ emissions for the bus trip from Louisville to Chicago?

    A bus trip from Louisville to Chicago generates an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

  6. What is the best bus company from Louisville to Chicago?

    According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5597 reviews.

  7. Which bus company has the best Wi-Fi from Louisville to Chicago?

    Based on Busbud reviews, the bus company Amtrak has the highest Wi-Fi rating with a score of 3.6.

  8. Which bus company has the best on-time performance from Louisville to Chicago?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Louisville to Chicago?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-27
$92
11-28
$98
Today
$204
11-30
$217
12-01
$79
12-02
$68
12-03
$59
12-04
$62
busbud logoThe cheapest trip from Louisville to Chicago was searched and found on Dec 3, 2025 with a price of $59

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Louisville to Chicago, as early as possible.

You can expect to pay from $59 to $217 for a bus ticket from Louisville to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $59 which is on 2025-12-03.

Usually Greyhound, Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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