Bus from Louisville to Chicago: Tickets & Timetables

Next bus departures

Next departures from Louisville to Chicago on 21 January
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.Bus
Louisville, KY
Chicago 95Th & Dan RyanCheapest
Greyhound Lines, Inc.Bus
Louisville, KY
Downtown Greyhound StationFastest
AmtrakBus
Louisville, KY
Chicago (Union Station), ILNo tags
Greyhound Lines, Inc.Bus
Louisville, KY
Downtown Greyhound StationNo tags
FlixBusBus
Louisville, KY
Downtown Greyhound StationNo tags

Last refresh of the prices: Today at 12:33 PM EST.

Get from Louisville to Chicago

This route is served by bus only

The journey takes about 7 hours 10 minutes, and with fares starting at just R 650, it presents an excellent value for a comfortable ride.

17bus per day
7h 10mAverage duration
434 kmDistance
11kgCO₂ emissions

Frequently asked questions about travelling from Louisville to Chicago by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

  1. How much is the bus ticket from Louisville to Chicago?

    The cheapest bus tickets from Louisville to Chicago start at R 650. The average price for this route is around R 894. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

  2. How long is the bus journey from Louisville to Chicago?

    The average bus journey time from Louisville to Chicago is 7h 10m, covering a distance of 434 km. The fastest bus gets you there in 5h 20m and is operated by FlixBus.

  3. Which bus companies service the Louisville to Chicago route?

    Several major bus companies operate on this route with 17 buses available per day, including services from Greyhound, FlixBus, Amtrak.

  4. What is the earliest and latest departure time for the bus from Louisville to Chicago?

    The earliest bus departs from Louisville to Chicago at 02:50. And the latest bus departs at 19:30.

  5. What are the CO₂ emissions for the bus trip from Louisville to Chicago?

    A bus trip from Louisville to Chicago produces an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

  6. What is the best bus company from Louisville to Chicago?

    According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5733 reviews.

  7. Which bus company has the best Wi-Fi from Louisville to Chicago?

    Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.

  8. Which bus company offers the most punctual service from Louisville to Chicago?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Louisville to Chicago?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
18/01
R 1 143
19/01
R 1 009
Today
R 916
21/01
R 790
22/01
R 605
23/01
R 756
24/01
R 639
25/01
R 756
busbud logoThe cheapest trip from Louisville to Chicago was searched and found on 22 Jan 2026 with a price of R 605

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Louisville to Chicago as early as possible.

You can expect to pay from R 605 to R 1 378 for a bus ticket from Louisville to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at R 605, which is on 2026-01-22.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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