Bus from Louisville to Chicago: Tickets & Schedules

Next bus departures

Next departures for Louisville to Chicago on November 29
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBusBus
Louisville, KY
Chicago 95Th & Dan RyanCheapestFastest
AmtrakBus
Louisville, KY
Chicago (Union Station), ILNo tags
Greyhound Lines, Inc.Bus
Louisville, KY
Downtown Greyhound StationNo tags
FlixBusBus
Louisville, KY
Downtown Greyhound StationNo tags
Greyhound Lines, Inc. + FlixBus
Bus
Louisville, KY
Chicago 95Th & Dan RyanNo tags

Last refresh of the prices: Today at 7:36 PM EST.

Get from Louisville to Chicago

This route is served by bus only

The journey takes about 7 hours 10 minutes and with fares starting at just $41, it presents an excellent value for a comfortable ride.

18bus per day
7h 10mAverage Duration
269 milesDistance
11kgCO₂ emissions

Frequently asked questions about traveling from Louisville to Chicago by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Louisville to Chicago?

    The cheapest bus tickets from Louisville to Chicago start from $41. The average price for this route is around $55. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Louisville to Chicago?

    The average bus trip duration from Louisville to Chicago is 7h 10m, covering a distance of 269 miles (434 km). The quickest bus can get you there in 5h 20m and is operated by FlixBus.

  3. Which bus companies service the Louisville to Chicago route?

    Several major bus companies operate on this route with 18 buses available per day, including services from Greyhound, FlixBus, Amtrak.

  4. What is the earliest and latest departure time for the bus from Louisville to Chicago?

    The earliest bus departs from Louisville to Chicago at 1:50am. And the latest bus departs at 7:30pm.

  5. What are the CO₂ emissions for the bus trip from Louisville to Chicago?

    A bus trip from Louisville to Chicago generates an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Louisville to Chicago?

    According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5597 reviews.

  7. Which bus company has the best Wi-Fi from Louisville to Chicago?

    Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.

  8. Which bus company has the most timely service from Louisville to Chicago?

    According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Louisville to Chicago?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/26
$151
11/27
$64
Today
$68
11/29
$72
11/30
$98
12/01
$52
12/02
$45
12/03
$41
busbud logoThe cheapest trip from Louisville to Chicago was searched and found on Dec 3, 2025 with a price of $41

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Louisville to Chicago, as early as possible.

You can expect to pay from $41 to $159 for a bus ticket from Louisville to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $41 which is on 2025-12-03.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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