Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Louisville Chicago recent customer reviews
The bus was 30 minutes late, there were too many people on board, leaving a couple to stand. Then the driver had to slam on his brakes and I don’t know how the standing people didn’t get thrown up front.
At one point the driver was getting on the interstate going the wrong way, until people started yelling at him. Absolutely not the best ride.
2 out of 5 stars
Reese W.
Mobile chargers and WiFi was not working at all despite the fact that same were informed to be working conditions
4 out of 5 stars
Muhammad Amir B.
This was the worst ride I have ever had. Negligence and just overall lateness. The trip should have taken 7 hours. It took over 11! Not acceptable
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 5607 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $87
Frequently asked questions about traveling from Louisville to Chicago by bus
What is the travel distance from Louisville to Chicago?
About 268 miles (432 km) separate Louisville and Chicago.
What are the departure and arrival stations when taking the bus from Louisville to Chicago?
The majority of buses traveling from Louisville to Chicago start their journey at Louisville Greyhound Bus Station and wind up at Downtown Greyhound Station. These are the main departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.
What are the best sights and things to do in Chicago?
Once in Chicago, you can start exploring the city and discover its surroundings. The top sights and things to do are Cloud Gate, Lincoln Park Conservatory, Museum of Contemporary Art, Shedd Aquarium and Museum of Science and Industry.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/23
$80
11/24
$75
Today
$118
11/26
$111
11/27
$57
11/28
$55
11/29
$75
11/30
$95
The cheapest trip from Louisville to Chicago was searched and found on Nov 28, 2025 with a price of $55
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Louisville to Chicago, as early as possible.
You can expect to pay from $55 to $154 for a bus ticket from Louisville to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $55 which is on 2025-11-28.
Usually Greyhound, Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from Louisville to Chicago was searched and found on Nov 28, 2025 with a price of $55
