Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Louisville Chicago recent customer reviews
The bus was 30 minutes late, there were too many people on board, leaving a couple to stand. Then the driver had to slam on his brakes and I don’t know how the standing people didn’t get thrown up front.
At one point the driver was getting on the interstate going the wrong way, until people started yelling at him. Absolutely not the best ride.
2 out of 5 stars
Reese W.
Mobile chargers and WiFi was not working at all despite the fact that same were informed to be working conditions
4 out of 5 stars
Muhammad Amir B.
This was the worst ride I have ever had. Negligence and just overall lateness. The trip should have taken 7 hours. It took over 11! Not acceptable
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 5611 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $87
Frequently asked questions about traveling from Louisville to Chicago by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Louisville to Chicago?
The cheapest bus tickets from Louisville to Chicago start from $41. The average price for this route is around $55. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Louisville to Chicago?
The average bus trip duration from Louisville to Chicago is 7h 10m, covering a distance of 269 miles (434 km). The quickest bus can get you there in 5h 20m and is operated by FlixBus.
Which bus companies service the Louisville to Chicago route?
Several major bus companies operate on this route with 18 buses available per day, including services from Greyhound, FlixBus, Amtrak.
What is the earliest and latest departure time for the bus from Louisville to Chicago?
The earliest bus departs from Louisville to Chicago at 1:50am. And the latest bus departs at 7:30pm.
What are the CO₂ emissions for the bus trip from Louisville to Chicago?
A bus trip from Louisville to Chicago generates an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Louisville to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5597 reviews.
Which bus company has the best Wi-Fi from Louisville to Chicago?
Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.
Which bus company has the most timely service from Louisville to Chicago?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Louisville to Chicago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/26
$151
11/27
$64
Today
$68
11/29
$72
11/30
$98
12/01
$52
12/02
$45
12/03
$41
The cheapest trip from Louisville to Chicago was searched and found on Dec 3, 2025 with a price of $41
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Louisville to Chicago, as early as possible.
You can expect to pay from $41 to $159 for a bus ticket from Louisville to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $41 which is on 2025-12-03.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.