Next departures for Los Angeles to San Luis Obispo on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Los Angeles Union Station
San Luis Obispo
CheapestFastest
Union Station
AMTRAK Station
No tags
Greyhound Lines, Inc. + FlixBus
Lankershim/Magnolia - North Hollywood
San Luis Obispo
No tags
Union Station
Cal Poly Vista Grande Dining Complex
No tags
UCLA
AMTRAK Station
No tags
Next departures for Los Angeles to San Luis Obispo on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
UCLA
AMTRAK Station
Cheapest
Los Angeles Union Station
San Luis Obispo
Fastest
UCLA
Cal Poly Vista Grande Dining Complex
No tags
Greyhound Lines, Inc. + FlixBus
Lankershim/Magnolia - North Hollywood
San Luis Obispo
No tags
Next departures for Los Angeles to San Luis Obispo on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Lankershim/Magnolia - North Hollywood
San Luis Obispo
Cheapest
Los Angeles Union Station
San Luis Obispo
Fastest
Union Station
AMTRAK Station
No tags
Union Station
Cal Poly Vista Grande Dining Complex
No tags
UCLA
AMTRAK Station
No tags
Next departures for Los Angeles to San Luis Obispo on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Los Angeles Union Station
San Luis Obispo
CheapestFastest
Union Station
AMTRAK Station
No tags
Greyhound Lines, Inc. + FlixBus
Lankershim/Magnolia - North Hollywood
San Luis Obispo
No tags
Union Station
Cal Poly Vista Grande Dining Complex
No tags
UCLA
AMTRAK Station
No tags
Next departures for Los Angeles to San Luis Obispo on November 29
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Union Station
AMTRAK Station
Cheapest
Los Angeles Union Station
San Luis Obispo
Fastest
Union Station
AMTRAK Station
No tags
Greyhound Lines, Inc. + FlixBus
Lankershim/Magnolia - North Hollywood
San Luis Obispo
No tags
Union Station
Cal Poly Vista Grande Dining Complex
No tags
Next departures for Los Angeles to San Luis Obispo on December 1
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
UCLA
AMTRAK Station
Cheapest
Los Angeles Union Station
San Luis Obispo
Fastest
UCLA
AMTRAK Station
No tags
Greyhound Lines, Inc. + FlixBus
Lankershim/Magnolia - North Hollywood
San Luis Obispo
No tags
UCLA
AMTRAK Station
No tags
Last refresh of the prices: Yesterday at 4:24 PM PST.
Compare 2 ways to go from Los Angeles to San Luis Obispo
We recommend taking the train
Among the sustainable travel choices, the train stands out as a good way to reach San Luis Obispo. The journey takes about 5 hours 25 minutes, and with fares starting at just $58, it presents an excellent value for a comfortable ride.
Based on 5607 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at $92
Amtrak Los Angeles San Luis Obispo recent customer reviews
The workers on the train and bus were great, as was the ride itself. However, the system was entirely too confusing and the information needed was not readily available.
At the Union station, the Amtrack worker behind the information desk just ignored me for over 10 minutes. This was at around 6pm, and the sign said that desk doesn't close until 10pm. The security guards were the ones helping people instead, and they were clearly used to doing that instead of focusing on security.
Also, when transferring from the train to the bus, there was no clear signage or directions as to where to go. About 30 of us almost boarded the wrong bus, as it was the only one there (our actual bus was 10-15 mins late) and the poor driver had no clear way to tell the entire crowd.
Overall, the workers were amazing (aside from the one at the help desk) but the system was way too confusing, especially considering the lack of help. Many of us were left feeling very lost and confused.
Based on 11439 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. FlixBus ticket prices on this trip start at $49
Based on 87393 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $75
Frequently asked questions about travelling from Los Angeles, US to San Luis Obispo by bus
How far is Los Angeles from San Luis Obispo?
The distance covered from Los Angeles to San Luis Obispo is 255 km (158 miles).
What are the departure and arrival locations for buses traveling from Los Angeles to San Luis Obispo?
Buses traveling this route start their trip at Ramirez Street bus stop, in Los Angeles, and end it at AMTRAK Station, in San Luis Obispo.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-22
$80
11-23
$89
Today
$96
11-25
$68
11-26
$129
11-27
$63
11-28
$89
11-29
$96
The cheapest trip from Los Angeles, US to San Luis Obispo was searched and found on Nov 27, 2025 with a price of $63
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Los Angeles, US to San Luis Obispo, as early as possible.
You can expect to pay from $63 to $391 for a bus ticket from Los Angeles, US to San Luis Obispo based on the last 2 days. You can expect to find the cheapest price for the trip at $63 which is on 2025-11-27.
Usually FlixBus, Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.